Selenium

Question 1

richest source of Se is

Answer 1

meat

Question 2

why does fish have low bioavailability of Se

Answer 2

mercury content

Question 3

selenium is absorbed in the

Answer 3

SI

Question 4

what vitamins enhance the absorption of Se

Answer 4

Vitamin A , C , E

Question 5

what inhibits the absorption of Se

Answer 5

phytate, heavy metals (mercury)

Question 6

selenium is bound to various proteins in order to travel through the blood such as ___ , __ and ____

Answer 6

VLDL
LDL
selenoprotein P

Question 7

selenium concentrates in the

Answer 7

thyroid gland
kidney
liver
heart
pancreas
muscle

Question 8

functions of selenium

Answer 8

cofactor in selenium dependent enzymes

immune function

Question 9

what are the selenium dependent enzyemes

Answer 9

iodothyronine deiodinases (IDI)
glutathione peroxidases (GPX)
selenoprotein P (SEL P)

Question 10

most of the biologically active T3 in teh circulation and inside cells is created by the removal of one iodine atom from ____ in a reaction catalyzed by selenium dependeny iodothyronine deiodinase enzymes`

Answer 10

T4

Question 11

selenium is essenetial for

Answer 11

normal growth

metabolism

Question 12

SEL P functions as a _______ for selenium

Answer 12

transport protein

Question 13

SEL P also acts as an ______ that protects endothelial cells from damage by reactive nitrogen species

Answer 13

antioxidant

Question 14

selenium is excreted in the

Answer 14

urine and feces

Question 15

selenium homeostasis is maintained by the

Answer 15

kidneys

Question 16

selenium deficiency related diseases

Answer 16

keshan

keshan beck

Question 17

keshan dz is a cardiomyopathy that affect young women and children in a selenium def ____

Answer 17

china

Question 18

keshan beck is characterized by the degeneration of ______

Answer 18

cartilage between joints

Question 19

keshan beck affects ages

Answer 19

5-13

Question 20

severe forms of keshan beck may result in

Answer 20

dwarfism

Question 21

clinical indications for selenium supplementation

Answer 21

HIV AIDS

Question 22

low levels of plasma selenium have ben associatd wtih a significantly increase risk of death from

Answer 22

HIV

Question 23

early signs of selenosis (selenium toxicity)

Answer 23

brittle nails
hair loss
dermatitis

Question 24

death due to acute selenosis results from what?

Answer 24

multiple organ failure

Question 25

the most freq reported sx of chronic selenosis are

Answer 25

hair and nail brittleness/loss
n/v/d
skin rashes
garlic breath
fatigue
irritability
nervous system abn

Question 26

selenium deficiency can trigger or worsen hypothyroidism in those with severe _____ deficiency

Answer 26

iodine

Question 27

asses ____ clippings for Se status

Answer 27

toenail clippings