Select Diseases Flashcards
The vast majority of microorganisms are _______. What follows is a list of diseases caused by one of the pathogenic microbes
nonpathogenic
Zoonotic diseases make up the
majority of diseases
How many new diseases are discovered per year?
5
When something is specific or unique to that disease, it’s
Pathognomonic
Top 8 zoonotic diseases in the US:
Influenza, Salmonella, West Nile, Plague, Rabies, Lyme, Brucellosis, SARS
Agent basically means
Caused by
Agent: Streptococcus pyrogens (G+ coccus)
Symptoms: Intense pain at infection site
Can spread up to 3 cm per hour
Necrotizing Fasciitis (flesh-eating bacteria)
Necrotizing Fasciitis (flesh-eating bacteria)
Agent: Streptococcus pyrogens (G+ coccus)
Symptoms: Intense pain at infection site
Can spread up to 3 cm per hour
Impetigo (pyoderma)
Agent: Staphylococcus aureus (G+ coccus)
Symptoms: Oozing pus-filled vesicles
Erysipelas may occur
Agent: Staphylococcus aureus (G+ coccus)
Symptoms: Oozing pus-filled vesicles
Erysipelas may occur
Impetigo (pyoderma)
What is Erysipelas?
When the infection spreads from the vesicles to the lymph nodes. When this happens, it’s no longer considered Impetigo.
Acne
Agent: Propionibacterium acnes (G+ bacillus)
Symptoms: Pustules within sebaceous glands
Agent: Propionibacterium acnes (G+ bacillus)
Symptoms: Pustules within sebaceous glands
Acne
Cat Scratch Fever
Agent: Bartonella henselae (Gram- bacillus)
Reservoir: Cat (mostly kittens)
Agent: Bartonella henselae (Gram- bacillus)
Reservoir: Cat (mostly kittens)
Cat Scratch Fever
Rocky Mountain Spotted Fever
Agent: Rickettsia rickettsii (Gram- bacillus)
Symptoms: Non-itchy spotted rash on palms/soles
Transmitted by a tick (reservoir)
Agent: Rickettsia rickettsii (Gram- bacillus)
Symptoms: Non-itchy spotted rash on palms/soles
Transmitted by a tick (reservoir)
Rocky Mountain Spotted Fever
Rocky Mountain Spotted Fever is most commonly seen in the South East/ Appalachian, including states such as:
Tennessee
North/South Carolina
Texas
Georgia
Mississippi
Alabama
Arkansas
Missouri
Florida
Kentucky
Louisiana
Gas Gangrene
Agent: Clostridium perfringens (G+ anaerobic endospore-forming bacillus)
Transmitted by endospore
Symptoms: Death of tissue (Necrosis)
Agent: Clostridium perfringens (G+ anaerobic endospore-forming bacillus)
Transmitted by endospore
Symptoms: Death of tissue (Necrosis)
Gas Gangrene
Death of tissue
Necrosis
Pseudomonas
Agent: Pseudomonas aeruginosa (G- bacillus)
Symptoms: Pyocyanin (blue-green coloring)
a Nosocomial Infection
Agent: Pseudomonas aeruginosa (G- bacillus)
Symptoms: Pyocyanin (blue-green coloring)
a Nosocomial Infection
Pseudomonas
Smallpox
Agent: Variola virus (DNA virus)
Transmission: Inhalation
What are the stages of disease for smallpox?
1- macule
2- papule
3- vesicle
4- pustule
5- crust
6- scar
What is the first disease to be eradicated globally?
Smallpox
Chickenpox
Agent: Varicella-zoster virus (DNA virus, enveloped)
Symptoms: Itchy rash
Transmission: Inhalation
With chickenpox, the _____ becomes ______(______) within ______ _____ _____
With chickenpox, the virus becomes latent (dormant) within sensory nerve endings
15-20% of individuals infected with chickenpox will experience a recurrence of a painful skin rash called ______. This is due to the _____ chickenpox found in sensory nerve endings. Typically occurs in the elderly. An interesting note about shingles is that…
15-20% of individuals infected with chickenpox will experience a recurrence of a painful skin rash called shingles. This is due to the latent chickenpox found in sensory nerve endings. Typically occurs in the elderly. An interesting note about shingles is that if vaccinated for chickenpox, you should never get shingles
Measles
Agent: Measles virus (RNA virus, enveloped)
Symptoms: Koplik’s spots
Botulism
Agent: Clostridium botulinum (Gram-positive, anaerobic, endospore-forming bacillus. Makes neurotoxins
Transmission of Botulism
Ingestion or wounds
3 different forms of botulism
- Foodborne (spores found in canned foods)
- Infant (develops from spores in intestines)
- Wound
Botulism: end result (foodborne, infant, and wound)
Paralysis
Floppy baby syndrome is caused by what disease
Botulism
Infants under 1 yr old should not consume
honey
Botulism: what does the neurotoxin actually do?
Prevents the release of Acetylcholine (ultimately leading to paralysis)
Clinical uses of Botulism
- Wrinkles
- Hyperhidrosis
- Migranes
Tetanus
Agent: Clostridium tetani (Gram-positive, anaerobic, endospore-forming bacillus. Makes a neurotoxin called tetanospasmin)
Symptoms: Lockjaw
What can be used to diagnose tetanus?
A Spatula test
Diagnosis/Treatment of Tetanus
Vaccine against tetanus called Tetanus Toxoid- neutralizes the toxin
How is tetanus transmitted
By an open wound
Poliomyelitis (Polio)
Agent: Poliovirus (RNA virus, naked)
Where do you still find polio today?
Pakistan and Nigeria
4 possible conditions of Polio (signs/symptoms)
Asymptomatic infections
Minor polio
Nonparalyic polio
Paralytic polio
Asymptomatic infections (polio):
almost 90% of cases
Minor polio
nonspecific symptoms like fever or headache
Nonparalytic polio
muscle spasms and back pain
Paralytic polio
produces paralysis by stopping action potential, recover in 6-24 months
The 4 possible conditions of polio all can lead to
Postpolio syndrome, a muscle deterioration 30-40 years after initial infection
Postpolio syndrome affects
80% of those who have had polio
Rabies
Agent: Rabies virus (RNA virus, enveloped)
Symptoms: Hydrophobia
Diagnosis: Postmortem confirmation of diagnosis
2 types of rabies
Furious and paralytic
Highest incidence of rabies occurs in
bats, skunks, raccoons foxes, and domesticated