Seizure mimics Flashcards
Benign myoclonus of infancy
Onset:
Often confused with:
How to exclude epilepsy:
Prognosis:
Onset: first year (typically 3-8 months)
Confused with: Spasms / Myoclonic seizures
How to exclude: Exam + EEG + development
Prognosis: abate by age 2
Shuddering attacks:
Description:
Onset:
Triggered by:
Prognosis:
Description: Tremor of head/arms/trunk
Onset: 4-6 months
Triggered by: Strong emotions
Prognosis: progressively decrease, resolve by age 10
Hyperekplexia
AKA:
Onset
Description
potential trigger
Affected receptor/gene
Treatment
-AKA: stiff baby syndrome or startle disease
- Onset: 6mo-6 years (peak 2-3 y)
- Description, Triad of:
- generalized stiffness
- Nocturnal myoclonus
- Tonic spasms w/ auditory or tactile stimuli
- Potential trigger: tapping tip of nose or glabella
- Mutation in Glycine Receptor (GLRA1 / GLRB2)
- Treatment: Clonazepam > VPA/LEV
PNES:
% of adult admissions for vEEG
- average time until diagnosis
- 25-40%
- Diagnosis often delayed by 7-10 years
PNES:
- Features associated with lower rate of remission (3)
- Features associated with Higher rate of remission (6)
Poorer prognosis:
- longer duration of illness
- abnormal neuropsych testing
- psychiatric comorbidities
Better prognosis:
- Male gender
- younger age at onset
- shorter duration of illnesss
- higher educational status
- Higher socioeconomic status
- minimal motor involvement
Define Jactatio captis nocturnal
- AKA
- Age range
- Description
- Specific location of movements
aka Rhythmic movement disorder
- usually in infancy and childhood
- involuntary, repetitive movements of large muscle groups immediately before and during sleep
- usually head or neck
Percentage of patients with narcolepsy who have
- sleep paralysis
- hypnogogic / hypnopompic hallucinations
- cataplexy
- automatic behaviors
- excessive daytime sleepiness
- Sleep paralysis: 25%
- Hypnogogic / hypnopompic hallucinations: 30%
- Cataplexy: 70%
- automatic behaviors: 50%
- excessive daytime sleepiness: 90%
Decades in which PNES are most likely to occur
third or fourth decade
Rate of incontinence in PNES
10-45%