Sedative Hypnotics

Question 1

Type of Melatonin Receptor Agonist

Answer 1

Ramelteon

Tasimelteon

Question 2

5HT receptor agonist

Answer 2

Buspirone

Question 3

New hypnotics

Answer 3

Eszopiclone
Zalepton
Zolpidem

Question 4

Given for BZD od

Answer 4

Flumazenil

Question 5

This is a major factor determines its rate of absorption

Answer 5

Lipophilicity

Question 6

Rapid absorption

Answer 6

Triazolam

Diazepam

Question 7

Parent drug of nordiazepam or drsmethyldiazepam

Answer 7

Diazepam
Chlordiazepoxide
Prazepam
Chlorazepate

Question 8

These drugs goes under alpha hydroxylation

Answer 8

Triazolam

Alprazolam

Question 9

This can increase serum levels of zolpidem

Answer 9

Cimetidine

Question 10

Specific to alpha 1 subunits

Answer 10

Zolpidem
Zaleplon
Eszopiclone

Question 11

Short acting.bzd

Answer 11

Zolpidem
Midazolam
Oxazepam
Triazolam

Question 12

Intermediate acting bzd

Answer 12

Lorazepam
Alprazolam
Temazepam
Estazolam

Question 13

Long acting bzd

Answer 13

Clonazepam
Chlorazepate
Flurazepam
Diazepam
Quazepam

Question 14

Sedative SE

Answer 14

Euphoria
Judgement imprairment
Loss of self restraint
Anterograde amnesia

Question 15

Hypnotic effect of zolpidem

Answer 15

Decrease rem sleep

Min. Effect on slow wave

Question 16

Hypnotic effect of zaleplon

Answer 16

Dec sleep onset latency
Min. Effect total sleep time
Nrem rem sleep