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Pharma B > Anti Microbials 2 > Flashcards

Anti Microbials 2 Flashcards

1
Q

Antibacterial activity of sulfonamides

A

Bacteriostatic
Poor against anaerobes
Pseduomonas resistant
Increase growth of rickettsia

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2
Q

What competes with paba

A

Dihydropteroate synthase

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3
Q

Short half life of sulfonamides

A

Sulfacystine
Sulfamethizole
Sulfaoxazole

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4
Q

Longest half life of sulfanomide

A

Sulfadoxine

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5
Q

Metabolism of sulfanomide

A

Liver via acetlylation and glucorination

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6
Q

Oral absorbable agent for UTI ane RTI

A

Sulfisoxazole and sulfamethoxazole

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7
Q

Given for toxoplamosis

A

Sulfadiazine with pyrimethamine

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8
Q

Associated with the use of 5ASA and ulcerative collitis

A

Sulfasalazine

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9
Q

The treatment for bacterial conjunctivitis and adjunctivr therapy for trachoma

A

Sodium sulfacetamide

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10
Q

AE hemolytic reaction with sulfonamides

A

Seen with G6PD

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11
Q

Tmp and smz are seen more in what body fluid

A

Prostatic and vaginal

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12
Q

This is used for acute UTI

A

Oral trimetophrim

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13
Q

Useful only in the treatment of lower UTI

A

First generation fluoroquinolones

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14
Q

Relaxation of positively supercoiler dna

A

Topoisomerase 2

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15
Q

Most active against gram negative especially pseudomonas aeruginosa

A

Ciprofloxacin

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16
Q

Given for ciprofloxacin resistant pneumonia

A

Gemifloxacin

17
Q

What is initially given for CAP

A

Levofloxacin

18
Q

What can cause impaired absorption of fluroquinolones

A

Antacids

19
Q

Fluoroquinolones causes photosensitivity

A

Lomefloxacin

Perfloxacin

20
Q

Contraindicated for pregnant women is.caused by

A

Arthropathy

21
Q

QT prolongation

A

Levofloxacin
Moxifloxacin
Gatifloxacin
Gemifolxacin

22
Q

This is potent against anaerobes, bacteriodes and clostridium

A

Metronidazole

23
Q

Clinical uses of brain abscess

A

Metronidazole

24
Q

Has an AE of disulfiram like effect

A

Metronidazole

25
Q

Produced by pseudomonas fluorescens

A

Muciprocin

26
Q

Acts as an cationic detergent

A

Polymixin B

27
Q

Narrow spectrum antibiotic

Treatment for c difficile

A

Fidaxomicin

28
Q

Antagonizes nalixidixic acid

A

Nitrofurantoin

29
Q

What is not combined with mrthenamine mandelate

A

Sulfonamide

Pharma B (8 decks)

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