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Derm Fitz > Section 27- Viral Diseases > Flashcards

Section 27- Viral Diseases Flashcards

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Dermatology Board Prep flashcards
1
Q

Self limited epidermal viral infection

Firmly pearly skin colored papules often umbilicated

A

Molluscum contagiosum

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2
Q

What type of MCV ( molluscum contagiosum virus) is responsible for >90% of cases?

A

MCV type 1

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3
Q

How can you get molluscum contagiosum?

A

Skin to skin contact

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4
Q

What host immune response is present around the mollusca that heralds spontaneous regression?

A

Inflammatory halo

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5
Q

Large intracytoplasmic inclusions in molluscum contagiosum

A

Henderson-Patterson bodies

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6
Q

Office based treatments in molluscum contagiosum

A 
Curretage
Cryosurgery 
Electrodessication
Canthardin
Imiquimod 5% cream
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7
Q

Erythematous exudative nodules most common in face, hands, extremities

May be edematous/bullous

Associated with contact with infected animals or fomites (sheep goat deer)

A

Human orf

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8
Q

Treatment for human orf

A

Resolves spontaneously after 4-6 weeks

Confere lifelong immunity

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9
Q

Solitary or multiple red or purple nodules at site of inoculation

From contact with bovine lesions or teat cups of milking machines

Resolves spontaneously

A

Milkers nodules

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10
Q

Red or brown dots on verruca represents:

A

Thrombosed dermal papilla capillary loops

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11
Q

Sign of resolution in palmar/plantar warts

A

Return of normal dermatoglyphics

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12
Q

Autosomal recessive

Flat topped papules, tinea versicolor like lesions, skin colored

Face hands arms trunk legs

A

Epidermodysplasia verruciformis

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13
Q

Treatment for verucca

A

Salicylic acid (17-40%) OD x 12 weeks

Imiquimod cream- 3x a week for not thickly keratinized sites

Hyperthermia (verruca plantaris) 45C x 20 mins 3x a week for 16 treatments

Cryosurgery, electrosurgery, CO2 laser

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14
Q

What sign?

Petechiae on soft palate

A

Forchheimer sign

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15
Q

Period of infectivity of rubella

A

End of incubation to disappearance of rash

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16
Q

Pink macules and papules initially on forehead spreading inferiorly to face trunk and extremities during first day

By 3rd day exanthem fades completely
Petechiae on soft palate, enlarged lymph nodes, arthritis in adults

A

Rubella

17
Q

Can have congenital rubella syndrome when pregnant has rubella in which trimester?

A

First

18
Q

Pathognomonic of measles

A

Koplik spots

19
Q

Cluster of tiny bluish white spots on red background after 2nd day of fever seen on buccal mucosa opposite premolars

A

Koplik spots

20
Q

Incubation 10-15 days
Prodrome- fever malaise URTI

4th febrile day- erythematous macules and papules on forehead at hairline and behind ears spreads centrifugally

Exanthem resolves in 4-6 days

A

Measles

21
Q

People infected with measles are contagious from:

A

Several days before onset of rash up to 5 days after lesions appear

22
Q

Cause of hand foot and mouth disease

A

Coxsackie virus A16

Enterovirus 71

23
Q

5-10 painful ulcerative oral lesions
Macules and papules that evolve into vesicles in palms and soles

Oral lesions: macules—grayish vesicles

High fever malaise diarrhea joint pains

A

Hand foot and mouth disease

24
Q

Erythema infectiosum is caused by

A

Human parvovirus B19

25
Q

Erythematous macules and papules that become confluent giving a lacy or reticulated appearance

Edematous confluent plaques on malar face that fade over 1-4 days

A

Erythema infectiosum

26
Q

Discrete nonpruritic erythematous monomorphic papules

Trunk is spared

Duration 2-8 weeks

A

Gianotti-Crosti Syndrome

Papular acrodermatitis of childhood

27
Q

Grouped vesicles arising on an erythematous base on keratinized skin or mucous membrane

A

HSV disease

28
Q

Positive Tzanck smear for HSV

A

Multinucleated giant acantholytic keratinocytes

29
Q

Antiviral treatment for HSV

A

Acyclovir
Valacyclovir
Famcilovir

30
Q

HSV infection of the tip of finger or thumb

Associated with painful neuritis in affected finger or forearm

A

Herpetic whitlow

31
Q

Period when varicella is contagious

A

Several days before varicella exanthem appears and until the last crop of vesicles

32
Q

Unilateral dysesthesia

Vesicular or bullous eruption limited to a dermatome

A

Herpes zoster

33
Q

Clinical stages of herpes zoster

A

Prodrome
Active infection
Post herpetic neuralgia

34
Q

Most common site of predilection of herpes zoster

A

Thoracic (>50%)

35
Q

Treatment for post herpetic neuralgia

A 
Gabapentin
Pregabalin
TCAs
Capsaicin cream
Nerve block
36
Q

High fever for 3 days

4th day fever disappears and small blanchable pink macules and papules 1-5mm in diameter in trunk and neck appears

A

Roseola infantum

37
Q

Etiology of roseola infantum

A

HHV 7

Derm Fitz (12 decks)

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