Section 1- Glands Flashcards

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1
Q

Key factors in the development of acne vulgaris

A

Follicular keratinization
Androgens
Proprionibacterium acnes

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2
Q

Blackheads are called

A

Open comedones

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3
Q

Whiteheads are called

A

Closed comedones

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4
Q

Neonatal acne is related to

A

Glandular development

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5
Q

Usually occurs in young women

Associated with extensive excoriations and scarring from emotional and psychological problems

A

Acne excoriée

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6
Q

Flares of acne on cheeks, chin and forehead due to leaning and pressure of sport gears

A

Acne mechanica

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7
Q

Severe cystic acne with more involvement of the trunk than the face

Coalescing nodules, cysts, abscesses and ulceration

A

Acne conglobata

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8
Q

Occurs primarily in teenage boys

Acute onset

Severe cystic acne with suppuration and ulceration

Malaise, fatigue, fever, elevated ESR

A

Acne fulminans

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9
Q

Acne like conditions are not diagnosed as acne because they do not have:

A

Comedones

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10
Q

If systemic isotretinoin treatment is required, these lab tests should be ordered beforehand

A

AST ALT
Triglycerides
Cholesterol levels

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11
Q

Long term goal of therapy for acne

A

Prevent scarring

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12
Q

Goal of therapy for acne

A

Remove plugging
Reduce sebum production
Treat bacterial colonization

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13
Q

Most effective oral antibiotic for moderate acne

A

Minocycline 50-100mg/day

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14
Q

This drug for acne inhibits sebaceous gland function and keratinization

A

Isotretinoin

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15
Q

Indications for oral isotretinoin

A

Moderate, recalcitrant and nodular acne

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16
Q

Concurrent tertracycline and isotretinoin may cause thid condition

A

Pseudotumor cerebri (benign intracranial swelling)

17
Q

Contraindication for use of isotretinoin

A

Pregnancy (teratogenic)

18
Q

Treatment for mild acne

A
Topical antibiotics (clinda, erythro)
Benzoyl peroxide gel (2,5,10%)
Topical retinoids (retinoic acid, adapalene, tazarotene)
-gradual increase 0.01-0.025-0.05%
19
Q

Treatment for moderate acne

A

Topicals plus oral antibiotics
Minocycline 50-100mg/day
Doxycycline 50-100mg BID

Oral isotretinoin

20
Q

Treatment for severe acne

A

Topicals plus systemic isotretinoin 0.5-1mg/kg (cystic, conglobate, refractory to treatment)

Most clear within 20 weeks

21
Q

Common chronic inflammatory acneiform disorder of the facial pilosebaceous units

Increased reactivity of capillaries leading to flushing and telangiectasia

A

Rosacea

22
Q

What stage of rosacea (Plewig and Kligman classification)

Persistent erythema with telangiectases

A

Stage I

23
Q

What stage of rosacea (Plewig and Kligman classification)

Persistent erythema, telangiectasia, papules and tiny pustules

A

Stage 2

24
Q

What stage of rosacea (Plewig and Kligman classification)

Persistent deep erythema, dense telangiectasia, papules, pustules and nodules

Rarely persistent “solid” edema on central face

A

Stage 3

25
Q

Prevention of rosacea

A

Marked reduction or elimination of alcohol and caffeine

26
Q

Topical treatment for rosacea

A

Metronidazole gel or cream 0.75 or 1% OD or BID

Ivermectin cream

27
Q

Systemic treatment of rosacea

A

Minocycline or doxycycline 50-100mg OD or BID

Tetracycline 1-1.5g/day until clear then 250-500mg OD

Metronidazole 500mg BID

28
Q

Maintenance treatment for rosacea

A

Minocycline or doxycycline 50mg OD or on alternate days

29
Q

For severe rosacea not responding to antibiotics, this can be given

A

Isotretinoin 0.5mg/kg per day

30
Q

For massive demodex infestation in rosacea, this drug can help:

A

Ivermectin 12mg PO single dose

31
Q

Treatment for periorificial dermatitis

A

Avoid topical glucocorticoids

Metronidazole 0.75% gel BID or 1% gel OD
Erythromycin 2% gel BID

Systemic- minocycline or doxycycline 100mg OD
Tetracycline 500mg BID until clear

32
Q

Sweat retention disorder

Excessive sweating —maceration and blockage of eccrine ducts

A

Miliaria

33
Q

Gustatory sweating where disrupted nerves for sweat abberrantly connect with salivsry nerves

A

Frey syndrome

34
Q

Management of hidradenitis suppurativa

A

Intralesional triamcinolone
Incision and drainage
Oral antibiotics- erytho, tetra, mino, clinda + rifampin
Oral isotretinoin- prevents follicular plugging

35
Q

Skin colored follicular pruritic papules in the axilla from plugging

A

Fox Fordyce disease