Section 1- Glands Flashcards

1
Q

Key factors in the development of acne vulgaris

A

Follicular keratinization
Androgens
Proprionibacterium acnes

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2
Q

Blackheads are called

A

Open comedones

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3
Q

Whiteheads are called

A

Closed comedones

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4
Q

Neonatal acne is related to

A

Glandular development

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5
Q

Usually occurs in young women

Associated with extensive excoriations and scarring from emotional and psychological problems

A

Acne excoriée

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6
Q

Flares of acne on cheeks, chin and forehead due to leaning and pressure of sport gears

A

Acne mechanica

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7
Q

Severe cystic acne with more involvement of the trunk than the face

Coalescing nodules, cysts, abscesses and ulceration

A

Acne conglobata

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8
Q

Occurs primarily in teenage boys

Acute onset

Severe cystic acne with suppuration and ulceration

Malaise, fatigue, fever, elevated ESR

A

Acne fulminans

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9
Q

Acne like conditions are not diagnosed as acne because they do not have:

A

Comedones

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10
Q

If systemic isotretinoin treatment is required, these lab tests should be ordered beforehand

A

AST ALT
Triglycerides
Cholesterol levels

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11
Q

Long term goal of therapy for acne

A

Prevent scarring

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12
Q

Goal of therapy for acne

A

Remove plugging
Reduce sebum production
Treat bacterial colonization

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13
Q

Most effective oral antibiotic for moderate acne

A

Minocycline 50-100mg/day

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14
Q

This drug for acne inhibits sebaceous gland function and keratinization

A

Isotretinoin

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15
Q

Indications for oral isotretinoin

A

Moderate, recalcitrant and nodular acne

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16
Q

Concurrent tertracycline and isotretinoin may cause thid condition

A

Pseudotumor cerebri (benign intracranial swelling)

17
Q

Contraindication for use of isotretinoin

A

Pregnancy (teratogenic)

18
Q

Treatment for mild acne

A
Topical antibiotics (clinda, erythro)
Benzoyl peroxide gel (2,5,10%)
Topical retinoids (retinoic acid, adapalene, tazarotene)
-gradual increase 0.01-0.025-0.05%
19
Q

Treatment for moderate acne

A

Topicals plus oral antibiotics
Minocycline 50-100mg/day
Doxycycline 50-100mg BID

Oral isotretinoin

20
Q

Treatment for severe acne

A

Topicals plus systemic isotretinoin 0.5-1mg/kg (cystic, conglobate, refractory to treatment)

Most clear within 20 weeks

21
Q

Common chronic inflammatory acneiform disorder of the facial pilosebaceous units

Increased reactivity of capillaries leading to flushing and telangiectasia

22
Q

What stage of rosacea (Plewig and Kligman classification)

Persistent erythema with telangiectases

23
Q

What stage of rosacea (Plewig and Kligman classification)

Persistent erythema, telangiectasia, papules and tiny pustules

24
Q

What stage of rosacea (Plewig and Kligman classification)

Persistent deep erythema, dense telangiectasia, papules, pustules and nodules

Rarely persistent “solid” edema on central face

25
Prevention of rosacea
Marked reduction or elimination of alcohol and caffeine
26
Topical treatment for rosacea
Metronidazole gel or cream 0.75 or 1% OD or BID Ivermectin cream
27
Systemic treatment of rosacea
Minocycline or doxycycline 50-100mg OD or BID Tetracycline 1-1.5g/day until clear then 250-500mg OD Metronidazole 500mg BID
28
Maintenance treatment for rosacea
Minocycline or doxycycline 50mg OD or on alternate days
29
For severe rosacea not responding to antibiotics, this can be given
Isotretinoin 0.5mg/kg per day
30
For massive demodex infestation in rosacea, this drug can help:
Ivermectin 12mg PO single dose
31
Treatment for periorificial dermatitis
Avoid topical glucocorticoids Metronidazole 0.75% gel BID or 1% gel OD Erythromycin 2% gel BID Systemic- minocycline or doxycycline 100mg OD Tetracycline 500mg BID until clear
32
Sweat retention disorder | Excessive sweating —maceration and blockage of eccrine ducts
Miliaria
33
Gustatory sweating where disrupted nerves for sweat abberrantly connect with salivsry nerves
Frey syndrome
34
Management of hidradenitis suppurativa
Intralesional triamcinolone Incision and drainage Oral antibiotics- erytho, tetra, mino, clinda + rifampin Oral isotretinoin- prevents follicular plugging
35
Skin colored follicular pruritic papules in the axilla from plugging
Fox Fordyce disease