Secretion and Exocytosis

Question 1

Exocytosis definition:

Answer 1

When a membrane-bound container fuses with the plasma membrane

Question 2

What are the consequences of exocytosis

Answer 2

-Contents of container released into extracellular space
-Plasma membrane expands with the membrane components supplies by the container

Question 3

What is the cargo moved around by exocytosis?

Answer 3

Soluble luminal and membrane proteins, ions, small molecules

Question 4

What are the types of exocytosis

Answer 4

Constitutive and regulated

Question 5

Constitutive exocytosis:

Answer 5

Vesicles will travel to, dock, and fuse with plasma membrane with no more signals

Question 6

Regulated exocytosis:

Answer 6

Vesicles will only fuse to plasma response to a signal

Question 7

What is responsible for lipid bilayer fusion?

Answer 7

SNARE proteins

Question 8

Structure of SNARE proteins

Answer 8

Alpha helices with a stripe of hydrophobic residues
helices then wrap around each other - looks like a twizzler

Question 9

How do SNARE proteins help with membrane fusion (generally)

Answer 9

Complementary sets on vesicle and target membrane
Basically form a little bundle. I’m unclear how this helps