Secondary Metabolites Flashcards

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1
Q

Define secondary metabolite

A

An organic compound produced by bacteria, fungi or plants which are not directly involved in the normal growth, development or reproduction of an organism

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2
Q

Give an example of a secondary metabolite

A

Antibiotics

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3
Q

Name two pathways by which antibiotics are made

A

BioWare

Cell-cell communication

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4
Q

Name the 5 things that antibiotics target

A
Protein synthesis
Nucleic acids
Cell wall
Cell membrane
Cell metabolism
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5
Q

Which antibiotics target protein synthesis?

A

Streptomycin
Tetracycline
Tryptomyosin

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6
Q

Which antibiotics target nucleic acid replication?

A

Rifampicin

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7
Q

Which antibiotics target the cell wall?

A

Penicillin

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8
Q

Which antibiotics target the cell membrane?

A

Tyrocidin

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9
Q

Which antibiotics target cell metabolism?

A

Sulphonamides

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10
Q

What are antibiotics?

A

Compounds that prevent the growth of microorganisms

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11
Q

What 3 variables can be manipulated in order to optimise the growth of secondary metabolites?

A

pH
Temperature
Carbon source

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12
Q

What was the name of the first antibiotic to be discovered?

A

Penicillin

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13
Q

What is the most common type of penicillin?

A

Penicillin G

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14
Q

What is the name of the microorganism-produced product of recombinant DNA that corrects dwarfism?

A

Human Growth Hormone

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15
Q

What is the name of the microorganism-produced product of recombinant DNA that is used for blood clotting?

A

Factor 8

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16
Q

What is the name of the microorganism-produced product of recombinant DNA that is used by diabetics ?

A

Insulin

17
Q

What is the name of the microorganism-produced product of recombinant DNA that is used to breakdown blood clots?

A

Tissue Plasminogen Activator (TPA)