Secondary Metabolites Flashcards
Define secondary metabolite
An organic compound produced by bacteria, fungi or plants which are not directly involved in the normal growth, development or reproduction of an organism
Give an example of a secondary metabolite
Antibiotics
Name two pathways by which antibiotics are made
BioWare
Cell-cell communication
Name the 5 things that antibiotics target
Protein synthesis Nucleic acids Cell wall Cell membrane Cell metabolism
Which antibiotics target protein synthesis?
Streptomycin
Tetracycline
Tryptomyosin
Which antibiotics target nucleic acid replication?
Rifampicin
Which antibiotics target the cell wall?
Penicillin
Which antibiotics target the cell membrane?
Tyrocidin
Which antibiotics target cell metabolism?
Sulphonamides
What are antibiotics?
Compounds that prevent the growth of microorganisms
What 3 variables can be manipulated in order to optimise the growth of secondary metabolites?
pH
Temperature
Carbon source
What was the name of the first antibiotic to be discovered?
Penicillin
What is the most common type of penicillin?
Penicillin G
What is the name of the microorganism-produced product of recombinant DNA that corrects dwarfism?
Human Growth Hormone
What is the name of the microorganism-produced product of recombinant DNA that is used for blood clotting?
Factor 8