second set HemeOnc MKSAP Flashcards
what meds cause B12 deficiency
Metformin
PPI
what absorpiton issues cause B12 deficiency
Crohns’-ileium affected
terminal ileium resection
partial gastric resection (parietal cells missing to make intrinsic factor)
pernicious anemia (ab agains parietal cells and/or Intrinsic factor)
reversal agent for dabigatran
idarucizumab
(if not available->do HD)
reversal agent for eliquis xarelto
PCC
Andexa alfa
duration of AC for provoked DVT
3-6mo
(extended for unprovked)
when is IVC filter indicated in a patient who had PE/DVT
if absolute contraindication to AC
in Multiple Myeloma, what is
-M protein spike?
-%plasma cells in bone marrow
->3g/dL
->10%
autoimmune hemolytic anemia 1st step in treatment
give them packed RBC
waldenstrom creates ___ spike which can cause ____ syndrome, in this case, tx is ______
M
hyperviscosity
plasmapheresis
what is first line in ITP
- mild
- severe
-mild: steroid 6wk
-severe: IVIG
TTP tx
plasma exchange
- replace adamts13 and put in multimers of vWB
____ criteria if low pre-test probability of PE, and if this scores zero, no CTA or d dimer needed
PERC
What is diagnosis if:
-positive antiglobulin test to antiC3(anticomplement 3) and NOT to to IgG
-with hemolysis
cold agglutinin
