2-uworld Flashcards
possible ITP, symptomatic, what are initial tests after blood smear?
HIV hepC
mild Acute chest syndrome give ___ vs mod-severe acute chest syndrome give ____
simple transfusion
exchange transfusion-target hg 10
if suspecting acute chest syndrome in SS, Xray/ct shows nothing on admit, does that rule out ACS?
NO, bcs you can have subsequent acute chest syndrome in later imaging!
first one doest rule it out
define Acute chest syndrom
new infiltrate in Xray/CT
AND
cough, or chest pain, or accessory muscle use, or dyspnea, or hypoxia/o2 req
etiology Acute chest synd
infection, fat emboli causing vasoocclusion, dehydration
mixing study corrects pt/ptt–meaning?
factor deficiency
mixing study does NOT correct pt/ptt–meaning?
there is an inhibitor of the factor
in asymptomatic, newly diagnosed hodgekin’s lymphoma, what should be concerned for?
fertility preservation (for the chemo/rads upcoming in future)
argatroban indicated if type2 HIT has _____ probability
intermediate to high
what are confirmatory HITT tests
serotonin assay (BEST)
platelet factor 4 antibody(ELISA)
other: heparin induced platelet aggregation assay
high probability scorea of HIT on 4T
6 or more
alternatives to argatroban for HITT
bivilarudin
fondaparinaux
MAHA always think of dx****
TTP/HUS/DIC
triggers of g6pd?
pathophys:
-infection
-medication ie bactrim, macrobid
-FAVA bean eating
-metabolic upset(DKA)
pathophys: oxidative stress to rbc–>hemolysis
how fast should priapism in Sickle cell crisis be corrected?
pathophys:
within 4 hours or irreversible damage
(otherwise IRREVERSIBLE ischemia)
pathophys: sickling causes blocked penile venous outflow
what is treatement of priapism in sickle cell crisis?
-IV hydration
-aspirate the corpus cavernosum
-inject epi/norepi in penile venous system to restore venous circulation
