1-uWorld Flashcards
how quickly to start ambulation after diagnosed with dvt
w/in 24 hrs!
lowers risk of PE, worsening dvt, mortality!!!
when to use the following for vWDisease
-desmopressin vs vWFactor prep
desmopressin: minor/mild vwd
vWfactor prep: mores severe symtpms and bleed
how is CLL diagnosed
flow cytometry
peripheral smear
Small cell lung cancer tx
chemo
autoimmune hemolytic anemia first line therapy
after giving pRBC,
FIRST line: steroids
autoimmune hemolytic anemia second line therapy
splenectomy
(after prbc and steroids)
tx for cold agglutinin
tx of cold +/- rituximab
CML Drug of choice**
tyrosine kinase inhibitor
ie imatinib
Multiple Myeloma drug of choice
lenalidomide
(immunomodulator)
Acute proMyelocytic Leukemia drug of choice
all trans retinoid acid WITH anthracycline based chemo
CML presentation
abdominal pain (splenomeg)
Weight loss
Bone pain
Anemia, LEUKOCYTOSIS, thrombocytosis
chromosome abnormality in CML
philadelphia chormosome
9,22 translocation
perioperatively, this____ should be done with Tamoxifen due to ____ reason
hold 2-4weeks
Risk of VTE
___ levels to determine eliquis xarelto activity
factor Xa levels
____ levels to determine dabigatran lactivity
thrombin time
in pleural fluid, pH is very sensitive as _____ pH goes with malignant fluid
low pH <7.3
pleural fluid studies that indicate empyema
LDH>1000
Glucose<60
pH<7.2
hairy cell leukemia Dx
Flow cytometry of Bone marrow biopsy
PERIPHRAL SMEAR shows HAIRY CELLS
hair cell leukemia tx
cladribine (cytotoxic chemo agent)
retic count is ___ in IDA and ACD
LOW
normal total B12 levels
200-400
normal hapto levels
male>13
female >12
normal fibrinogen level
200-400
