3-uworld

Question 1

test/dx for carcinoid syndrome

Answer 1

24hr urine HIAA

MRI abdomen for mets

ECHO for tricuspid regurg/involve

Question 2

tx for carcinoid syndrome

Answer 2

octreotide

Question 3

average time btwn exposure to radiation and resultant Breast cancer development is _____ years

____ should be done as surveillance

Answer 3

15

annual mammogram

Question 4

Strategy for PREVENTION of Tumor Lysis Syndrome for HIGH risk patient

Answer 4

IV hydration
(helps prevent AKI from renal stones-ca-ph, and uric acid)
+
5days-1wk of prophylactic RASBURICASE or ALLOPURINOL(preferred)

Question 5

electrolyte disturbance to define Tumor Lysis syndrome

Answer 5

Hyperkalemia
Hyperphosphatemia
HypOCalcemia
Uric acidosis>8

Question 6

who is high risk for Tumor lysis

Answer 6

ALL, AML, Burkitt lymphoma

Question 7

patient comes with symptoms of DVT, you get leg u/s which is negative, what is the next step?

Answer 7

get D-dimer—->if high, GET REPEAT U/S

if D-dimer low, NO DVT

Question 8

5 things that correlate with survival time in patients with advanced cancer**

___________ is the MOST IMPORTANT predictor of patient’s prognosis

Answer 8

Dysphagia-1mo
Cognitive status-1mo
Anorexia-2mo
Xerostomia (dry mouth)-2mo
Dyspnea-1mo

dependency vs not in ACTIVITIES OF DAILY LIVING

Question 9

if symptoms occur within ____ days post transplant, it is considered acute graft vs Host disease and not CHRONIC which can occur _____

Answer 9

100

ANYTIME

Question 10

tx for acute graft vs host 1st line

Answer 10

Glucocorticoids+

Question 11

in sickle cells: chronic transfusions Q4-6wks helps prevent ______

Answer 11

stroke

Question 12

most common presentation of pancoast tumor is _____ and most common cancer form is _____

Answer 12

shoulder pain

non small cell lung cancer

Question 13

Smouldering Myeloma:
____ Mspike
____ Bone marrow clonal cells
____ organ damage

Answer 13

> 3 Mspike
>10% Bone marrow clonal cells
NO END ORGAN DAMAGE

Question 14

MGUS:
____ Mspike
____ Bone marrow clonal cells
____ organ damage

Answer 14

<3 Mspike
<10%Bone marrow clonal cells
NO END ORGAN DAMAGE

Question 15

Multiple Myeloma:
____ Mspike
____ Bone marrow clonal cells
____ organ damage

Answer 15

> 3 Mspike

> 10% Bone marrow clonal cells W/ end organ
-OR-
60% bone marrow clonal cells w/o end organ

THERE IS END ORGAN DAMAGE!!!

Question 16

pentad of TTP

Answer 16

anemia-shistocytes
thrombocytopenia
renal fail

FEVER
neuro-AMS

Question 17

tetrad of HUS

Answer 17

anemia-shistocytes
thrombocyto
Renal fail

Question 18

can Multiple Myeloma be diagnosed without end organ damage?

Answer 18

yes, if clonal cells in Bone marrow >60%