Schizoprenia, MacIntyre Flashcards

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1
Q

delusion

A

fixed, false belief non consistent w/ cultural or religious background
bizarre or non bizarre

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2
Q

hallucination

A

false sensory perception not assoc with real external stimuli
olfactory common!

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3
Q

do personality disorders have hallucinations

A

no

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4
Q

DDX psychosis

A

SLE, acute intermittent porphyria, major depressive disorder, bipolar disorder, seizures, schizophrenia, substance intoxication, delirium, dementia, adverse drug reaction

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5
Q

4 As of schizophrenia

A

Associations
Autism
Ambivalence
Affect

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6
Q

demopgraphics schizophrenia

A

men=women
onset late teens to late 20s
men earlier than women

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7
Q

signs schizophrenia

A

wide range mental disturbances
increased suicide risk
more likely to be victim of violence
Dx of exclusion

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8
Q

what is prodromal period schizo

A

first break can be mild to severe

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9
Q

dx of schizophrenia

A
>2 for >1 mo
delusions
hallucinations
disorganized speech
grossly disorganized or catatonic behavior
negative Sx
Signs persits for at least 6 mo
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10
Q

what must be ruled out to Dx schizophrenia

A

schizoaffective, mood disorders, substances, general medical conditions, autism spectrum

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11
Q

positive Sx of schizo

A

hallucinations and delusions
usually auditory hallucinations!!!
disorganized speech/behavior

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12
Q

negative Sx schizo

A

lack of motivation
affective blunting
cognitive blunting
impaired social funcitnoing and social withdrawal

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13
Q

reason for genetic consideration schizo

A

inc in monozygotic twins

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14
Q

imaging in schizo

A

enlarged 3rd and lateral ventricles

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15
Q

which area of brain affected in schizophrenia

A

prefrontal Cx connections (last cortical area to develop)

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16
Q

NT thought to be involved in schizophrenia

A

DA
serotonin
glutamate

17
Q

1st line Tx in schizophrenia

A

antipsychotics

18
Q

monitor what if on antipsychotic

A

movement disorders, dystonia, akathisia, tremor, rigidity, tardive dyskinesias
neuroleptic malignant syndrome
anticholinergic effects
sedation
metabolic consequences (DM, weight gain, dyslipidemia)

19
Q

what is akathisia

A

inability to sit still

20
Q

risks with clozapine

A

agranulocytosis– restricted use

can dec suicidality!!!!!!!

21
Q

what occurs with noncompliance to meds in schizo

A

decompensation, brain tissue may be lost with each relapse

22
Q

schizophreniform disorfer

A

Sx of schizophrenia but only last

23
Q

schizoaffective disorder

A

both schizophrenia and depression or bipolar illness

24
Q

Dx schizoaffective disorder

A

2 weeks schizophrenia Sx in absence of mood Sx
AND
presence of mood Sx for substantial part of lifetime illness course

25
Q

Tx schizoaffective disorder

A

psychosis with antipsychotics
mania with mood stabilizers
depression with antidepressants

26
Q

brief psychotic disorder

A

psychosis > 1 day but

27
Q

Tx brief psychotic disorder

A

antipsychotics

28
Q

what is a type of brief psychotic disorders

A

post partum psychosis

29
Q

postpartum psychosis

A

emergency!!!
keep mother and baby safe
mother may have bipolar Hx

30
Q

delusional disorder

A

> 1 mo of delusion
behavior and function usually not affected
W>M mid late life

31
Q

Tx delusional disorder

A

psychotherapy, poor response to antipsychotics