Depressive Disorders, Weiss Flashcards
depressive disorders more common in M or W
W
age onset depresstion
40 y.o average
cause depression
unknown
causative factors for depression
biological
genetic
pyschosocial
biological factors for depression
dysregulation with NT
neuroendocrine dysregulation of adrenal or thyroid axis
growth hormones etc
genetic factors for depression
pattern unknown
1st degree relatives 2-10 x more likely
50% monozygotic twins
psychosocial factors for depression
stressful events premorbid personality factors learned helplessness cognitive theory psychodynamic theory early childhood trauma
what is dysthymia
peristent depressive disorder that is chronic low grade
does not respond well to antidepressants
tyeps of depressive disorders
major, single major, recurrent persistent depressive disorder substance. med induced premenstrual dysphoric disorder depressive from another medical condition
Dx depression
significant distress with funcitonal impairment
not due to direct physiological effects of a substance
major depressive disorder
at least a depressed mood or anhedonia(lack of interest of pleasurable activity)
at least 2 weeks
at least 4 Sx
clinical features depression
depressed mood marked dec interest dec/inc appetite, weight change sleep disturbance psychomotor agitaiton/retardation loss of E guilt, worthlessness poor concentration, indecisiveness recurrent thoughts of death, suicidal thoughts
mental status exam general description
appearance, hygiene level cooperativeness eye contact posture pyschomotor agitation/retardation
mental status exam
speech perceptual disturbances thought content suicidal thoughts orientation memory concentration attention judgement, insight, reliability
what general medical conditions can lead to depression
infections, endocrine disorders, inflammatory disorders, neuro disorders, vitamine deficiencies
neoplasms