Schizophrenia (Structural Abnormalities) Flashcards

1
Q

What was the initial treatment approach for schizophrenia in early psychology?

A

Psychological treatments

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2
Q

What method did psychologists first use to study the brains of schizophrenics?

A

Post mortems

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3
Q

What are the two main hypotheses regarding the cause of brain changes in schizophrenia?

A

Neurodegenerative and neurodevelopmental

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4
Q

In neurodevelopmental illness, what factors contribute to improper brain development?

A
  • Genes
  • Prenatal development
  • Events in childhood
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5
Q

What is expected in neurodegenerative illnesses regarding brain changes?

A

Few brain changes at the start, with progressive worsening over time

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6
Q

What structural difference is observed in the brains of schizophrenics compared to controls?

A

Larger brain ventricles

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7
Q

What study compared ventricle sizes in chronic schizophrenics and controls?

A

Weinberger et al (1979)

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8
Q

What percentage of schizophrenics were found outside the control group’s range in ventricle size?

A

40%

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9
Q

What does cortical atrophy refer to?

A

Loss of neurons in the brain

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10
Q

What did Vita et al (1988) find regarding brain atrophy in schizophrenics?

A

33% of schizophrenics had atrophy

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11
Q

What might cause the reduction in brain volume in schizophrenia according to Feinburg (1982)?

A

Reduction in connections between neurons

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12
Q

What is reversed cerebral asymmetry in the context of schizophrenia?

A

The right hemisphere is larger than the left

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13
Q

What did Luchins et al (1979) find regarding the asymmetry of the brain in schizophrenics?

A

Increased frequency of reversals in both the frontal and occipital lobes

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14
Q

Which area of the brain is responsible for facial recognition and is often damaged in schizophrenia?

A

Temporal lobe structures

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15
Q

What did Jibiki (1991) find regarding visual processing in schizophrenics?

A

Disruptions to visual processes in the occipital lobe

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16
Q

What did Andreasen et al (1994) discover about the thalamus in people with schizophrenia?

A

Lower metabolic rate

17
Q

What conclusion did Oblai et al (2011) reach about brain volume in schizophrenia?

A

Clear progression with brain volume decreasing over time

18
Q

What did Chan et al (2011) find about individuals at high risk for schizophrenia?

A

They had smaller brain volume and enlarged ventricles before showing symptoms

19
Q

What is a limitation of studies on schizophrenia according to the evaluation?

A

Not all structural abnormalities are present in all schizophrenics

20
Q

What is a criticism of biological theories regarding schizophrenia?

A

Highly nomothetic and deterministic

21
Q

Fill in the blank: The brain contains support cells called _______.

A

Glial cells

22
Q

True or False: Schizophrenia is solely caused by structural abnormalities.

A

False

23
Q

What is one implication of biological theories for treatment development?

A

They are useful for developing treatments

24
Q

What factor complicates the interpretation of research findings on schizophrenia?

A

Many schizophrenics are on antipsychotic medication during research