Schizophrenia and Other Psychotic Disorders Flashcards

1
Q

When is the peak onset time for schizophrenia?

A
  • late adolesence and early adulthood

- negative sx have a poor prognosis

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2
Q

+ sx of schizophrenia

A
  • sx added to the presentation
  • typically present in the active phase
  • Delusions
  • Hallucinations
  • Catatonia
  • Agitation
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3
Q

What is loosening of associations

A
  • when connections among the pts ideas are absent or obscure

- listeners may feel as if understanding of the pts thoughts had been suddenly lost

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4
Q

What does the form of though look like in schizo ppl?

A
  • loosening of associations
  • poverty of content and speech
  • thoguht blocking: internal interruption in pts speech/thoughts
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5
Q

What does the content of thought llok like in schizo ppl?

A
  • delusions of persecution, reference, influence
  • thought broadcasting
  • grandiose delusions, somatic delusions
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6
Q

what is the schizo affect like?

A

-blunted/flat/inappropriate

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7
Q

Negative sx of schizophrenia

A
  • sx that appear missing from the presentation
  • typically present in the residual phase
  • affective flattening
  • apathy
  • social withdrawal
  • anhedonia: they don’t have any fun
  • poverty of thought
  • content of speech
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8
Q

How long do the sx for schizo have to be present?

A

-6 months!!!!!!***** importante

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9
Q

What are some things we have do be able to rule out when making the dx of schizo?

A
  • seizure disorders
  • metabolic disorders
  • thyroid df
  • brain tumor
  • neurosyphillis
  • street drug use****
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10
Q

psychiatric ddx for schizo

A
  • delusional disorder
  • mood disorders
  • OCD
  • personality disorders
  • “normal adolescence”
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11
Q

When are ppl with schizo born?

A

-higher rates in pts born in winter and early spring months

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12
Q

What will schizo eyes look like?

A

-saccadic eye movements, not smooth when reading over something

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13
Q

What will brain imaging look like in schizo?

A
  • structural volume reduction in cortical structures

- enlarged ventricles (3rd and 4th)

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14
Q

What were some of the big sx that they have to have for most of 1 month?

A
  • delusions
  • Hallucinations
  • Disorganized speech
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15
Q

are schizos more likely to commit homicide?

A

-nah

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16
Q

What is the single leading cause of death in schizos?

A

-suicide

17
Q

What drug to we give suicidal ppl?

A
  • clozapine

- be sure to check for neutropenia

18
Q

What things do we have to look for in the schizophrenia, Catatonic type?

A
  • motoric immobility as evidenced by catalepsy or stupor
  • excessive motor activity (apparently puroposeless and not influenced by external stimuli)
  • extreme negativism or mutism
  • peculiarities of voluntary movement such as posturing, stereotyped movements, prominent mannerisms or prominent grimacing
  • Echolalia or echopraxia
19
Q

Schizophrenia treatments

A
  • hospitalization
  • group therapy
  • individual psychotherapy
  • community treatment
  • self-help programs
  • pharmacology
  • ECT
  • Benzos for catatonic disorder
20
Q

What do we have to do pharamcologically for schizo?

A
  • block the DA receptors!!!
  • first gen antipsychotics: haloperidol, fluphenazine
  • lorazepam calms them down
21
Q

What are some first generation antipsychotics adverse effects?

A
  • EPS syndromes

- NEuropleptic malignant syndrome

22
Q

What do the second generation antipsychotics do?

A
  • block DA receptors AND affect serotonin activity
  • Clozapine (agranulocytosis… watch out)
  • Risperidone
  • Olanzapine
  • Quetiapine
  • Ziprasidone: QTc prolongation
  • Iloperidone
  • Aripiprazole: partial DA agonist
23
Q

If it ends with “pine”, what side effect must we worry about?

A
  • weight gain

- p….. pig

24
Q

What is Schizoaffective disorder?

A
  • Uninterrupted period of illness with either a major depressive episode or manic episode concurrent with sx that meet criterion A for schizophrenia
  • Same period of illness, have been delusions or hallucinations for at least 2 weeks in the absence of prominent mood sx
25
Q

What is brief psychotic disorder?

A
  • Presence of at least … of the following:
  • delusions
  • hallucinations
  • disorganized speech
  • grossly disorganized or catatonic behavior
  • Duration of an episode of the disturbance is at least 1 day and no more than 1 month*****, with eventual return to premorbid level of functioning
26
Q

What is Schizophreniform?

A
  • Meets criteria A, D, and E for schizophrenia

- an episode of the disorder lasts at least 1 month but less than 6 months

27
Q

What is delusional disorder?

A
  • delusions of at least 1 month’s duration,
  • has never met criterion A for schizophrenia
  • apart from the impact of the delusion, functioning is not impaired and behavior is not odd or bizarre
28
Q

If schizo, what time line are we looking for?

A

-> 6 months

29
Q

Schizophreniform time

A

-1-6 months

30
Q

Brief psychoti disorder

A

-<1 month

31
Q

What is schizoid

A

-very inroverted and voluntarily withdrwas from social interactions

32
Q

What is schizotypal?

A

-schizoid sx + magical thinking and odd behavior

33
Q

What is schizophrenia?

A

schizotypal+ psychosis

34
Q

What is schizoaffective?

A

-Schizophrenia+ mood disorder