Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Psychiatry HK > Schizophrenia > Flashcards

Schizophrenia Flashcards

1
Q

neurotransmitter responsible for schizophrenia

A

dopamine (too much)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

most likely time to be diagnosed with schizophrenia

A

early adulthood

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

what is schizophrenia

A

chronic relapsing condition of distorted thought, emotion, perception and behaviour

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

what are the 2 groups of symptoms in s

A

positive and negative

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

positive symptoms

A

delusions
hallucinations
thought disorder

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

negative symptoms

A 
apathy
lack of volition (will power)
social withdrawal
cognitive impairment 
catatonia
loss of interest
self-absorbed attitude
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

most common hallucination in schizophrenia

A

third person auditory - giving a running commentary

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

what are thought disorders

A 
thought insertion
throught broadcasting 
thought withdrawal 
knight's move thoughts
neologisms
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

diagnostic criteria for schizophrenia

A

1 positive symptom or 2 negative symptoms

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

what are Schneider’s first rank symptoms

A

symptoms very suggestive of schizophrenia:
auditory hallucinations (running commentary)
thought disorder
somatic hallucinations
delusional perception
passivity phenomena

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

how long must symptoms last for

A

1 month continuously

6 months if on/off

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

differentials for psychosis

A 
drug induced 
depressive 
mania with psychosis 
schizoaffective disorder 
delirium
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

common drug that can cause psychosis

A

cannabis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

manifestation of manic psychosis

A

delusions of grandeur, special ability, persecution, religiosity

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

what is schizoaffective disorder

A

patient experiences symptoms of an affective disorder (depression or mania) and psychosis within days of each other

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

how to differentiate delirium from schizophrenia

A

elderly

triad of acute onset, inattention with fluctuating course, altered consciousness/disorganised thinking

17
Q

if medication is required in delirium, what should be given

A

haloperidol

18
Q

when should antipsychotic medication be commenced

A

at diagnosis of schizophrenia/psychosis

19
Q

psychological interventions in schizophrenia

A

CBT
manage substance misuse
family therapy and support groups

20
Q

what are the two groups of antipsychositcs

A

typical (older)

atypical (newer)

21
Q

examples of typical antipsychotics

A

chlorpromazine

haloperidol

22
Q

examples of atypical antipsychotics

A

olanzapine
risperidone
quetiapine
clozapine

23
Q

what receptors do atypical antipsychotics work on

A

D2 antagonists and 5HT2A antagonists (more this)

24
Q

what receptor do typical antipsychotics work on

A

D2 agonists

25
Q

which type of antipsychotic is first line

A

atypical

26
Q

why are atypicals used first line

A

better side effect profile

27
Q

what atypical is first line

A

olanzapine

28
Q

what is next line management after olanzapine

A

another atypical
then a typical
then clozapine

29
Q

SE of typical antipsychotics (D2 blockade)

A

extra-pyramidal (tardive syndromes, dyskinesias, parkinsonianism, neuroleptic malignant syndrome)
hyperprolactinaemia
sedation
long QTc

30
Q

what part of brain is affected in extra-pyramidal side effects

A

dorsal striatum

31
Q

SE of atypical antipsychotics (5HT2 blockade)

A

metabolic syndromes

32
Q

SE of histamine receptor block

A

sedation

increased appetite

33
Q

side effect of muscarinic block

A

PARASYMPATHETIC

think eyes, salivary glands, bowel, bladder

34
Q

when is clozapine used

A

resistant to other treatment

35
Q

side effects of clozapine

A 
sedation 
agranulocytosis (patient should come in if got a sore throat)
myocarditis (if stopped suddenly)
gastroparesis
weight gain
hypersalivation
36
Q

what monitoring is required in clozapine treatment

A

weekly for first 6 months
fortnightly for next 6 months
every 4 weeks thereafter
one month after stopping treatment

37
Q

what anti-psychotics are not safe in pregnancy

A

clozapine

olanzapine

Psychiatry HK (21 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions