genetics Flashcards
1
Q
genetic defect in huntingtons
A
CAG repeat coding for poly-glutamine
2
Q
effect of poly-glutamine
A
toxic effect on cells causing neuronal loss
3
Q
what is anticipation
A
more repeats as it is passed down generations
worse condition as gets passed down
4
Q
when are symptom onset for huntingtons
A
adulthood
5
Q
what happens to brain structure in Alzheimer’s disease
A
brain atrophy
enlarged ventricles
shrinkage of hippocampus
