Schizophrenia Flashcards
Schizophrenia
A psychotic disorder marked by severely impaired thinking, emotions & behaviour
What symptoms do they experience
Positive and negative
Positive symptoms
Enhance their typical experience, an addition to their normal experience
Examples of positive symptoms
- Hallucinations: distorted view of perception
- Delusions: irrational beliefs
- Disorganised speech: abnormal thought processes
- Catatonic behaviour: reduced reaction to the environment
Types of delusions
- Paranoid delusions: a belief the person is being followed
- Delusions of grandeur: they think they are famous or have special abilities
- Delusions of reference: person on TV is stalking them
Examples of negative symptoms
- speech poverty: there is abnormally low levels of frequency, quality of speech
- avolition: reduction interest,desires,goals
Inability to cope with day-to-day tasks - anhedonia: loss of interests or pleasure in all activities
- affective flattening: reduction in emotional expression
What are the two classification systems for mental disorders
- DSM-V: US
- ICD-10: Europe
What are the requirements for a diagnosis by the DSM-V
- 2 or more symptoms
What are the biological explanations
- Genetic explanations
- Dopamine hypothesis
- Neural correlates
Genetic explanations:running in families
Gottesman found that the closer the genetic link between you and someone with SZ, the higher chance of you developing illness
Genetic explanations: candidate genes
There isn’t one single gene for SZ but a collection of gene locations associated with a higher risk of developing SZ, so SZ is polygenetic
Dopamine hypothesis (high levels)
Symptoms of SZ are due to high levels of dopamine in the subcortex
Hyperdopaminergia (high levels of dopamine) in the Broca’s area may lead to auditory hallucinations.
Dopamine hypothesis (low levels)
Hypodopaminergia (lower levels of dopamine) in the frontal cortex are linked to negative symptoms like avolition and speech poverty.
What research supports the dopamine hypothesis
In meta analysis including 212 studies Leucht found that drug treatments that work by normalising dopamine levels were more effective than a placebo . This treatment directly influences dopamine systems supports the dopamine hypothesis.
Psychological explanations
- Family dysfunctions
- Cognitive explanations