Scaly Dermatoses Flashcards

1
Q

Dandruff: Sx, Location, Appearance, Time Course

A
  • Sx: often itchy
  • Location: scalp only (even/spares bald areas)
  • Appearance: flakes are thin, white/gray, minimal skin inflammation
  • Time Course: appears in puberty, peaks in early adulthood, lessens with older age
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Seborrheic Dermatitis: Sx, Location, Appearance, Time Course

A
  • Sx: often itchy
  • Location: scalp, face, trunk (patchy)
  • Appearance: scales are thin, yellow/oily, underlying plaques of red/inflamed skin
  • Time Course: chronic, relapsing/remitting
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

SD in Infants “Cradle Cap”: Sx, Location, Appearance, Time Course

A
  • Sx: does not disturb sleep or feeding, rarely itchy
  • Location: scalp is most common (cradle cap) face, trunk, or diaper areas (patchy)
  • Appearance: crusts or scales are thin, yellow/oily, underlying plaques of red/inflammed skin
  • Time Course: begins ~3 wks old, resolves before 12 mo old
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Plaque Psoriasis: Sx, Location, Appearance, Time Course

A
  • Sx: itchy or painful, non-derm complications are common
  • Location: scalp, trunk, extremities, extensor surfaces (elbow/knee), symmetrical
  • Appearance: bleeding spots if scales are removed, thick, silvery white, red underlying plaque with sharp borders
  • Time Course: chronic, relapsing/remitting
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Etiology

A

• Dandruff & seborrheic dermatitis: Unknown
– Colonizing microbes, Malassezia yeast
– Immune hyperactivity, inflammation

• Psoriasis: Unknown
– Genetics
– Immune hyperactivity, inflammation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Triggers

A

• Dandruff & Seborrheic Dermatitis:
– Dry or cold climate
– Physical or emotional stress

• Psoriasis:
– Dry or cold climate
– Physical or emotional stress 
– Skin irritation or injury
– Infections
– Alcohol or tobacco use
– Some medications (ex: beta blockers, lithium)
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Risk Factors

A
• Dandruff & Seborrheic Dermatitis: 
– HIV or AIDS
– Parkinson’s Disease
– Epilepsy
– Recent stroke or heart attack
– Depression
– Eating disorders

• Psoriasis:
– Family history

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Exclusions for OTC Medical Self-Treatment

A
  • Age < 2 years
  • Worsening or no improvement after 2 weeks of appropriate OTC medication use
  • Involvement of eyes or inner ear canal
  • Extensive disease (>5% body surface area)
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Non-pharmacological Treatment

A

• Dandruff & Seborrheic Dermatitis:
– Residue free, non-medicated shampoo or soap
– Avoidance of triggers

• Psoriasis:
– Residue free, non-medicated shampoo or soap
– Avoidance of triggers
– Sunlight or UV therapy
– Emollients, lubricants, or warm soaks for dry, cracked skin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

OTC Treatment Options

A

Antifungals

  • Kills yeast, Malassezia
  • Pyrithione zinc, selenium sulfide, ketoconazole

Cytostatics

  • Reduce skin cell turnover
  • Coal tar

Keratolytics

  • Soften and break up flakes
  • Salicylic acid, sulfur

Corticosteroids

  • Reduce inflammation
  • Hydrocortisone
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Dandruff OTC Treatment

A
  • Shampoos are the preferred product form
  • Usual dose: Apply for 5 minutes 2-3x weekly until sx control, then decrease to q1-2 weeks

– Antifungals: 1st choice (good efficacy, few AE’s)
– Coal tar: Useful in refractory cases (more significant AE’s)
– Keratolytics: Useful in select cases (patient preference)
– Hydrocortisone: Not used for dandruff

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Seborrheic Dermatitis OTC Treatment

A

• Same options, usually dosed more aggressively:
– Daily (1st wk), then 2-3x weekly (4 wks), then weekly
• Product selection depends on area:
– Scalp & hairy areas: Shampoo preferred > cream or gel
– Skin of face & body: Ointment or cream preferred
• Hydrocortisone preferred for acute exacerbations

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Cradle Cap Treatment

A

• Emphasize non-pharm therapy, refer to MD if severe or no response after 2 weeks
– Frequent shampooing with non-medicated shampoo
– Emollients (petrolatum, vegetable oil, mineral oil, baby oil) to soften & loosen scales, may apply and leave overnight
– Gentle brushing to remove scales

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Psoriasis OTC Treatment

A

• Only mild cases can be self-treated
• Product selection depends on disease phase:
– Chronic phase (scales): Coal tar, salicylic acid
– Acute phase (flares): Hydrocortisone

• Antifungals generally not useful
– Possible exception: Chronic, mild cases of the scalp

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Monitoring

A
• Therapeutic
– Resolution of symptoms (already discussed) 
• Toxic
– Adverse effects (already discussed)
• Follow-uptime
– Dandruff: 1-2 months
– Seborrheic dermatitis: 1-2 weeks 
– Psoriasis: 1-2 weeks
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Psoriasis: More to look out for…

A

• Psoriatic arthritis (likely >30% of patients)
– Joint pain or soreness, see MD
– Nail pitting, ridging, or color change, see MD
• Depression or suicidality
– Depressed mood, lack of enjoyment, see MD

17
Q

Administration Technique

A

Shampoos:

  1. Rinse & wash hair and scalp with non-medicated, residue-free shampoo to remove oil and dirt
  2. Apply medicated shampoo, massage into scalp
  3. Leave in for 5-10 minutes (contact time is key!)
  4. Rinse off thoroughly (decreases staining)
  5. Avoid eyes, mucous membranes, or broken skin

Skin Products:

  1. Gently cleanse area
  2. Apply product sparingly (only enough to cover)
  3. Do not wash off afterwards
  4. Avoid eyes, mucous membranes, or broken skin
18
Q

Dosing Instructions

A

• Initial therapy
– Short-term high dosing frequency
– Goal is to alleviate symptoms

• Maintenance therapy
– Long-term intermittent dosing
– Goal is to prevent relapse