SC - Mechanisms of Mutation Flashcards
1
Q
Define heritable and transient mutations?
A
Heritable- Can be transferred from one generation to the next (germ-line cell)
Transient- Occur for a short period of time (somatic cell)
2
Q
What are 3 examples of point mutations?
A
- Insertions
- Deletions
- Substitutions
3
Q
What occurs during a translocation mutation?
A
A segment from one chromosome is transferred to another
4
Q
What can lead to point mutations?
A
Unrepaired mistakes in DNA synthesis
5
Q
What are mutagens?
A
Any physical, chemical or biological agent that raises the frequency of mutations above the spontaneous rate
6
Q
What are the 2 major classes of transposons?
A
- CLASS I (Retrotransposons)
- CLASS II (DNA Transposons)
7
Q
Can transposons be destructive?
A
Yes