SARS-CoV-2 and COVID-19

Question 1

What is the coronavirus structure?

Answer 1

has surface viral proteins (spike glycoprotein) (S)
membrane glycoprotein (M)
nucleocapsid protein (N)
envelope

Question 2

What is the target of spike glycoprotein?

Answer 2

cell surface receptor ACE2

Question 3

What are some potential transmission routes for SARS-CoV-2

Answer 3

aerosol (droplets)
direct contact
direct contact with contaminated surfaces

Question 4

Where does initial replication of SARS-CoV-2 take place?

Answer 4

upper respiratory tract

Question 5

How does a primary viremia occur?

Answer 5

establishment of infection and replication in the lung pneumocytes

Question 6

How does viremia dissemination continue in the body?

Answer 6

via the blood stream where another cycle continues

Question 7

What is a major contributor to SARS-CoV-2?

Answer 7

age is a risk factor

Question 8

What are clinical characteristics of post-COVID-19 condition?

Answer 8

brain (headache or other cognitive impairment)
lungs (cough, shortness of breath)
skin (bruising, rashes)
nose/nasal cavity (loss of taste or smell)
heart (pounding heart, heart failure)
kidney (risk of acute kidney injury)

Question 9

What is the first most distinct variant?

Answer 9

S D614G