cellular immunity Flashcards

1
Q

Primary and secondary lymphoid tissues form the…?

A

Cellular immunity

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2
Q

Antibodies are also known as…?

A

Humoral immunity

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3
Q

Primary lymphoid organs main role is…?

A

Development and maturation

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4
Q

Secondary lymphoid organs main role is..?

A

Development + interaction with pathogens and exogenous antibodies

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5
Q

Main types of cells are…?

A

T cells and B cells

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6
Q

Other cells useful in cellular immunity is…?

A

Eosinophil, macrophages, large granular lymphocytes, phagocytes, basophils, mast cells, mononuclear, natural killer cells, platelets

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7
Q

B cells are known for their…?

A

Production of antibodies.

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8
Q

T cells, large granular lymphocytes and mononuclear phagocytes are a type of?

A

cytokine

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9
Q

Basophils, mast cells and platelets are known as… and are used for?

A

auxiliary cells

inflammatory mediators

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10
Q

The main phagocytes are…?

A

Mononuclear, eosinophils and neutrophils

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11
Q

What are phagocytic cells used for?

A

Killing of cells coated with antibody or complement

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12
Q

Why are non lymphoid cells important?

A

Have phagocytic activity

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13
Q

What is antigen presentation?

A

Display of antigenic determinants to lymphoid cells which have specific receptors

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14
Q

What are the major cells associated with acquired immunity?

A

T cells
B cells
NK cells

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15
Q

The role of T cells and NK cells in acquired immunity are…?

A

Combat viral infections

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16
Q

What is the role of B cells in acquired immunity…?

A

Production of plasma cells and antibodies

17
Q

T cells mature in the…?

A

Thymus

18
Q

B cells and NK cells mature in the…?

A

Bone marrow

19
Q

What do T and B cells possess that NK cells do not?

A

An antigen specific receptor

20
Q

What is the difference in antigen specific receptors between B and T cells?

A

B cells = modified antibody molecule

T cells = T Cell Receptor (TCR)

21
Q

How is different cell types distinguished?

A

Cell surface proteins known as Cluster of Differentiation (CD)

22
Q

What are the two major groups of T cells?

A

CD4+ and CD8+

23
Q

What is the role of CD4+ T cells?

A

Helper cells –> They activate B cells or macrophages

24
Q

What is the role of CD8+ T cells?

A

Cytotoxic cells and kill virally infected cells.

25
Q

What is the Major Histocompatibility Complex (MHC)?

A

Contain and secrete mediators which play a role in immunity

26
Q

What machine can separate cells based on surface markers?

A

Flow cytometer / Fluorescent Activated Cell Sorting (FACS)