cellular immunity Flashcards
Primary and secondary lymphoid tissues form the…?
Cellular immunity
Antibodies are also known as…?
Humoral immunity
Primary lymphoid organs main role is…?
Development and maturation
Secondary lymphoid organs main role is..?
Development + interaction with pathogens and exogenous antibodies
Main types of cells are…?
T cells and B cells
Other cells useful in cellular immunity is…?
Eosinophil, macrophages, large granular lymphocytes, phagocytes, basophils, mast cells, mononuclear, natural killer cells, platelets
B cells are known for their…?
Production of antibodies.
T cells, large granular lymphocytes and mononuclear phagocytes are a type of?
cytokine
Basophils, mast cells and platelets are known as… and are used for?
auxiliary cells
inflammatory mediators
The main phagocytes are…?
Mononuclear, eosinophils and neutrophils
What are phagocytic cells used for?
Killing of cells coated with antibody or complement
Why are non lymphoid cells important?
Have phagocytic activity
What is antigen presentation?
Display of antigenic determinants to lymphoid cells which have specific receptors
What are the major cells associated with acquired immunity?
T cells
B cells
NK cells
The role of T cells and NK cells in acquired immunity are…?
Combat viral infections
What is the role of B cells in acquired immunity…?
Production of plasma cells and antibodies
T cells mature in the…?
Thymus
B cells and NK cells mature in the…?
Bone marrow
What do T and B cells possess that NK cells do not?
An antigen specific receptor
What is the difference in antigen specific receptors between B and T cells?
B cells = modified antibody molecule
T cells = T Cell Receptor (TCR)
How is different cell types distinguished?
Cell surface proteins known as Cluster of Differentiation (CD)
What are the two major groups of T cells?
CD4+ and CD8+
What is the role of CD4+ T cells?
Helper cells –> They activate B cells or macrophages
What is the role of CD8+ T cells?
Cytotoxic cells and kill virally infected cells.
What is the Major Histocompatibility Complex (MHC)?
Contain and secrete mediators which play a role in immunity
What machine can separate cells based on surface markers?
Flow cytometer / Fluorescent Activated Cell Sorting (FACS)
