Sarcoidosis Flashcards

1
Q

ILD

A

Disease involving the terminal bronchi and alveoli

Impaired gas exchange, restrictive pattern

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2
Q

Aetiology

A

Disease of unknown cause
Less common in smokers
Common in afro-carribean’s
Multiple system involvement

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3
Q

Clinical Presentation

A

Acute - erythema nodosum, bilateral hilar lymphadenopathy, arthritis, uveitis, fever

Chronic - same as above + alveolitis (due to lung infiltrates), peripheral lymphadenopathy, hypercalcaemia

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4
Q

Investigations

A
CXR - diagnostic, look for bilateral hilar lymphadenopathy
CT scan 
Biopsy 
PFT - restrictive pattern 
Blood tests - increased calcium
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5
Q

Pathology

A

Non caseating granulomas

type IV hypersensitivity

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6
Q

Management

A

Acute - self limiting, supportive treatment

Chronic - oral steroids, immunosuppression

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