Biochemistry Flashcards
Sensitivity
percentage of people with a disease with a positive test for that disease
Specificity
percentage of people without a disease who have a negative test for that disease
Prevalence
A measure of how common the disease is in the population of people who have been tested for the disease
People with disease + all the people who have been tested
Acidosis
increase H+ conc
Alkalosis
Decrease H+ conc
Respiratory component
pCO2
Metabolic component
HCO3-
Respiratory acidosis
Increase in H+ conc
Increase in pCO2
EG: choking, COPD
Respiratory alkalosis
Decrease in H+ conc
Decrease in pCO2
EG: PE, mechanical over-ventilation, anxiety, pain
Metabolic acidosis
Increase in H+ conc
Decrease in HCO3 (as it’s used up by the H+)
EG: over production of acid
Metabolic alkalosis
Decrease in H+ conc (loss of acid, alkali surplus)
Increase in HCO3
EG: vomiting (loose acid causing an increase in bicarbonate)
Compensation
Too much H+ , lungs blow off CO2 to restore ratio
Too much CO2, kidneys get rid of H+ to restore ratio.
If primary mechanism is resp then compensatory mechanism will be metabolic
Resp compensation for metabolic acidosis
Too much H+
Compensate by blowing off CO2.
Resp compensation occurs quickly
Metabolic compensation for resp acidosis
too much CO2
get rid of H+
Metabolic compensation occurs slowly
Fully compensated
pH is within normal ranges
Partially compensated
pH is outwit normal range
pO2
If pO2 is in the information and it is LOW then it suggests the RESP system isn’t working well
