Idiopathic Pulmonary Fibrosis Flashcards
1
Q
ILD
A
Disease involving the terminal bronchi and alveoli
Impaired gas exchange, restrictive pattern
2
Q
Aetiology
A
Most common
Common in smokers
Disease of unknown cause
Secondary causes - BREAST CA (bleomycin, radiation, EAA, asbestos etc)
3
Q
Clinical presentation
A
Progressive breathlessness Dry cough Malaise Weight loss Symptoms gradually worsen
4
Q
Clinical signs
A
Finger clubbing
Bilateral fine inspiratory crackles
5
Q
Investigations
A
CXR - bilateral infiltrate
CT scan - key test. honey combing, fibrotic shadowing
Biopsy - not always needed
6
Q
Pathology
A
UIP (usual interstitial pneumonia)
Heterogeneous fibrosis in alveolar walls
Honey combing
7
Q
Management
A
Oxygen
Lung transplant
Steroids and immunosuppressants don’t work
