sarcoidosis Flashcards
1
Q
define sarcoidosis
A
idiopathic granulomatous disease
2
Q
risk factors for sarcoidosis
A
- women
- 20-40y
- afro-caribbean descent
3
Q
pathophysiology of sarcoidosis
A
Immune system ‘overreacts’ causing granulomas to form in different organs of the body
4
Q
symptoms of sarcoidosis
A
- Fever
- fatigue
- dry cough
- dyspnoea
- uveitis
- Lupus pernio (purple rash/nodules on cheeks and shins - seen in chronic sarcoidosis)
5
Q
3 investigations for sarcoidosis
A
- bloods
- chest x ray
- biopsy - diagnostic
6
Q
what do bloods for sarcoidosis show
A
raised ACE and Ca+
7
Q
what does chest x ray for sarcoidosis show
A
bilateral hilar adenopathy + pulmonary infiltrates
8
Q
what does biopsy for sarcoidosis show
A
NON caseating granulomas
9
Q
how to treat early stages of sarcoidosis
A
In early stages can be self resolving
10
Q
how to treat symptomatic sarcoidosis
A
corticosteroids
11
Q
what is Lofgren syndrome
A
a subset of sarcoidosis
triad of:
1. fever
2. erythema nodosum
3. bilateral hilar adenopathy
12
Q
A
