Sarcoidosis Flashcards

1
Q

What is sarcoidosis?

A

Multisystem chronic inflammatory condition

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2
Q

What does SARCOID stand for?

A
Skin
Arthritis
Respiratory
Cardiac
Ocular
Intracranial
Derangement of liver and renal function
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3
Q

What skin problem is present?

A

Erythema nodosum

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4
Q

What respiratory problems are present?

A

Bilateral hilar lymphadenopathy, pulmonary infiltrates

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5
Q

What cardiac problems are present?

A

Heart block, VT, HF

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6
Q

What ocular problem is present?

A

Anterior uveitis

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7
Q

What intracranial problems are present?

A

Chronic meningitis, seizures, neuropathy

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8
Q

What liver/renal problems are present?

A

Hepatic granuloma, hypercalcaemia

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9
Q

What is Lofgren syndrome?

A

An acute form of sarcoidosis with BHL, erythema nodosum and arthralgia

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10
Q

What blood results would you expect?

A

Raised ESR, raised serum ACE

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11
Q

What would you see on hisotlogy?

A

Non-caseating granulomas

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12
Q

How do you do a bone profile?

A

Calcium, corrected calcium, albumin, total protein and alkaline phosphatase

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13
Q

What imaging would you do?

A

A CXR

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14
Q

Where would you biopsy?

A

Transbronchial

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15
Q

How do you treat stages I-III?

A

Remission likely

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16
Q

What is stage I?

A

BHL

17
Q

What is stage II?

A

BHL and infiltrates

18
Q

What is stage III?

A

Infiltrates alone

19
Q

How do you treat stage IV?

A

Prednisolone +/- bone protection

20
Q

What is stage IV?

A

Pulmonary fibrosis