Sara Gordon Flashcards
Top three sexually transmitted disease i the us?
1) Chlamydia
2) Gonorrhea
3) Syphilis
What are the three species of Chlamydia and which diseases do they cause?
1) C trachomatis (#1 sex transmitted disease) → Mucous membrane disease (genitals, oral mucosa, infant pneumonia)
2) C pneumoniae → respiratory (pharyngitis, brochitis, pneumonia)
3) C psittaci → psittacossis (birds) Mild fever, headache, dry cough, sometimes pneumonia)
Which species is responsible for Gonococcal stomatitis?
Neisseria gonorrhea g- intracellular diplococcus
How is gonococcal stomatitis transmitted?
Sexual and maybe kissing an infected person
What are the symptoms of gonococcal stomatitis?
Usually asymptomatic,
pharyngitis, tonsilitis, fever, swollen lymph nodes
What is the causative agent for syphilis?
Treponema pallidum, corkscrew, motile, need darkfield/ fluoresc to see
What are the three stages of syphilis? What is the likelihood of progression? When is it transmittable?
primary, secondary, tertiary ⅔ progress onto next stage ⅓ clears on its own
Transmittable at any stage, also can be passed to infant during pregnancy, any stage
What are the the clinical manifestations of primary syphilis? when does it appear?
1-3 weeks post contact,
1) Chancre (macule→papule→ulcer) on the site of inoculation
2) regional lymphadenopathy (rubbery, painless, bilateral)
3) blood test may not be + during early primary syphilis
What are the clinical features of secondary syphilis?
Dissemination of spirochetes
3-6 weeks after 1 chancre
persists weeks - months
blood tests are highers in titer in this stage!
- Skin rash (hands and feets!!)75-100%
- Lymphadenopathy
- malaise
- Mucous pathes (6-30%)
- condylomata lata (10-20%)
- Hair loss-5%
What is condyloma lata?
secondary syphilis,
grayish papules on infected genitals (ass. with skin rash)
What is latent syphilis?
May occur between primary and secondary, and after secondary
no clinical lesions
What are the clinical signs of tertiary syphilis? Likelihood of progression?
30% of untreated progress within 1-20 yrs
- Gummas -gummatous lesions
- cardiovascular syphilis
- neurosyphilis
List three major oral manifestations of tertiary syphilis?
- gumma - palate midline, tongue or tonsils. Bone destruction -palatal perforation!
- Luetic glossitis -was linked to cancer, but no because it was tx with arsenic lol
- painless swelling of the parotid gland-rare
Describe gamma and what disease is it linked to? where does it classically appear?
gummatous necrosis = tertiary syphilis
Gummatous necrosis at the center of granulomas -variation of coagulation necrosis
classical appearance - hard palate
What are the orofacial features of congenital syphilis?
- Rhagades (infected fissures, oral comissures)
- Frotal bossing
- Perforation of palate (bacteria→tissue damage)
- Saddle nose
- Mucous patches (secondary and congenital)
- Hutchinson triad (deaf, blind, Malformed teeth→hutchinson’s incisors, mulberry teeth)
- short maxilla
What is the causative agent for cat scratch disease?
Bartonella henselae
g- bacilus, 90% bc contact with cat, reactive lympadenitis
Whats the causative agent for diphtheria?
Klebs-Loeffler bacterium/ Corynebacterium
Whats the causative agent for diphtheria?
Klebs-Loeffler bacterium/ Corynebacterium
What are the three systemic manifestations of diphtheria?
Interference with cardiac conduction
paralyses of palate
kidney failure
also-diphtheric membrane in throat can suffocate
What is diphtheria?
Necrotizing upper resp tract infection
How does oral TB happen?
Coughing up infected sputum
Someone with an active lung TB →infected sputum→cut open wound in mouth(tongue or tooth extracted socket)
What are the most frequent oral locations of oral TB?
Tip and lateral margins of the tongue
hard and soft palate
tooth socket after extraction
How does oral TB progress?
clinically can resemble malignancies
red papules→painful soft punched out shallow ulcer
What is scrofula ?
TB in the neck involving skin and lymph nodes
