Salivary Glands and TMJ Flashcards

1
Q
\_\_\_\_\_ is involved to some degree in all of the
following functions:
 Speech
 Mastication
 Taste
 Swallowing
 Digestion
Protection
Buffering
Antimicrobial action
Maintenance of tooth integrity
Soft tissue repair
A

Saliva

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2
Q

_____: protein thought to be necessary for growth and

maturation of taste buds.

A

 Gustin:

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3
Q

____ degrades starch

A

Salivary amylase

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4
Q

_____: a protein that raises pH of dental plaque after exposure
to fermentable carbohydrates

A

Sialin:

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5
Q

Function of saliva:
 Lubrication protects lining mucosa from noxious stimuli,
bacterial toxins, and minor trauma
 Washing action to rid mouth of non-adherent bacteria
 Clearance of sugars from mouth

A

Protection

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6
Q

Function of saliva:
 Prevents potential pathogenic bacteria from colonizing the
mouth (most require an acidic pH)
 Buffering of microbial acids (bicarbonate & phosphate ions)

A

Buffering

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7
Q

______ hydrolyzes bacterial cell walls

A

Lysozyme:

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8
Q

______ binds free iron and thereby deprives bacteria

of an essential nutrient

A

Lactoferrin:

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9
Q

______ causes bacterial clumping (agglutination)

A

Salivary IgA:

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10
Q

Function of saliva:
 Calcium and phosphate ions facilitate mineralization of
tooth surface

A

Maintenance of tooth integrity

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11
Q

Function of saliva:
 Epithelial growth factor
 Clotting factor

A

Soft Tissue Repair

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12
Q

_____ cells dictate differentiation of oral
epithelium which, in turn, proliferates and grows into
the underlying mesenchyme

A

Ectomesenchymal

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13
Q

Alveoli develop into _____

A

acinar cells

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14
Q

Epithelial cords develop into ____

A

ducts

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15
Q

FGF + EGF + Terminal Bulb Cells give rise to what 3 types of cells?

A

Acinar cells, myoepithelial cells, and duct cells

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16
Q

The parotid and submandibular glands begin to form during the ____ week of embryonic development

A

6th

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17
Q

The sublingual gland

initiating development during the _____ week of embryonic development

A

8th

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18
Q

The minor salivary glands begin to form by the ___ week of embryonic development.

A

10th

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19
Q

What is the Hierarchy of ducts starting at the level of

the secreting unit (acinus)?

A
 Intercellular canaliculus
 Intercalated duct
 Striated duct
 Excretory duct
 (a.k.a. collecting duct)
 Terminal excretory duct
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20
Q

Crypts between cells that contain villi

A

Intercellular Canaliculus

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21
Q

____ are lined with cuboidal cells that could be stem cells

A

Intercalated Duct

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22
Q

Associated with terminal end pieces (acini) and intercalated ducts.

A

Myoepithelial Cells (a.k.a. Basket Cells):

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23
Q

____ contain microvilli involved in electrolyte resorption; Na and Cl are absorbed and K and HCO3 are secreted

A

Striated Duct

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24
Q

_____ is a smooth duct with no villi; no secretion or absorption here

A

Excretory (collecting) duct

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25
Q

What is the name of the duct for the parotid gland

A

Stetson’s duct

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26
Q

What is the name of the duct for the submandibular gland

A

Wharton’s duct

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27
Q

What is the name of the duct for the sublingual gland

A

Bartholin’s duct

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28
Q
\_\_\_\_ gland:
Pure serous secreting gland
 Responsible for 20% of unstimulated
 salivary flow
 Salivary gland enlargement occurs
 in parotitis (mumps), Sjögrens syndrome,
 bulimia nervosa, anorexia nervosa, benign
 and malignant neoplasia.
A

Parotid gland

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29
Q

____ gland:
 Mixed seromucous gland (i.e., predominately serous
with mucous contributions)
 Responsible for 60% of unstimulated salivary flow.
 Serous demilunes

A

Submandibular gland

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30
Q

_____ gland:
Mixed mucoserous gland (i.e., predominately mucous secreting)
 Responsible for 10% of unstimulated salivary flow
 Serous demilunes

A

Sublingual gland

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31
Q

Minor salivary glands account for ___% of unstimulated

salivary flow

A

10%

32
Q

Most minor salivary glands are _____ secreting

A

mucous

33
Q

Minor salivary gland: Pure serous glands associated with circumvallate papillae

A

• von Ebner’s

34
Q

Minor salivary gland: Mucoserous glands located on ventral surface at tip of tongue

A

• Blandin-Nuhn

35
Q

Minor salivary gland: Mucous glands associated with the pharyngeal tonsils

A

• Weber’s

36
Q

Minor salivary gland: Mucous glands found in the mandibular retromolar area

A

• Carmalt’s

37
Q

– product secreted into blood and affects other cells;

no duct system

A

• Endocrine

38
Q

– secrete product onto a surface; usually has a duct

A

• Exocrine

39
Q

– little/no damage to secreting cells (salivary glands)

A

• Merocrine

40
Q

– partial injury to secreting cells (mammary/sweat

glands)

A

• Apocrine

41
Q

– total destruction of secreting cells (sebaceous

glands)

A

• Holocrine

42
Q

• Not a pathologic lesion
• Represent ectopic sebaceous
glands

A

Fordyce’s Granules

a.k.a. Fordyce Spots

43
Q

The result of trauma that severs the duct resulting in extravasation of
mucin into the surrounding soft tissues
 Most common site of occurrence are the lips, tip of the ventral surface
of the tongue and soft palate
 Characterized by a accumulation of mucin containing numerous
foamy histiocytes surrounded by granulation tissue

A

Salivary gland mucocele

44
Q

A term used to designate a mucocele that occurs in
the floor of the mouth. most often involve
the sublingual salivary gland.

A

Ranula

45
Q

 Chronic, systemic autoimmune disease
 80% to 90% of cases occur in middle aged females
 Xerostomia, xerophthalmia or keratoconjunctivitis sicca
 Parotid gland swelling due to lymphocytic & plasma cell infiltrate

A

Sjögren’s Syndrome

46
Q

Benign tumor that accounts for 53% to 77% of
parotid gland tumors; 44% to 68% of subman-
dibular gland tumors; and 38% to 43% of minor
salivary gland tumors
 Histology:
• Well circumscribed and encapsulated
• Tissue derived from mixture of ductal and
myoepithelial cells
• Keratinizing squamous cells and mucous
producing cells are also present

A

Mixed Tumor aka Pleomorphic Adenoma

47
Q

 One of the most common salivary gland
malignancies
 Most commonly involves the parotid gland.
Consequently, pain or facial nerve palsy
may develop
 Histology:
• Composed of a mixture of mucous producing
cells and squamous epidermoid cells.
• Abundant cellular pleomorphism and a tendency
to form cystic areas within the tumor cell mass

A

Mucoepidermoid Carcinoma

48
Q

___ are involved in proprioception in TMJ

A

Ruffini corpuscles

49
Q

____ are involved in dynamic mechanoreception (chewing) in TMJ

A

Pacinian corpuscles

50
Q

____ are involved in static mechanoreception in TMJ

A

Golgi tendon organs

51
Q

____ are involved in pain in TMJ

A

Free nerve endings

52
Q

The TMJ is classified as a ____ joint:

A

synovial sliding-ginglymoid

hinged

53
Q

____ joints permit movement between two bones.

A

Synovial

54
Q

Each bone of TMJ is covered by _____ cartilage.

A

hyaline

55
Q

The two bones of TMJ are united and surrounded by a ____ thereby creating a joint cavity.

A

fibrous capsule

56
Q

The joint cavity is filled with ______ (approximately
1mL) that is derived from villus cells which line the internal
surface of the capsule

A

synovial fluid

57
Q

_____ separates the bones of TMJ

A

fibrous disc

58
Q

Both the condylar neck and head develop by

_____ ossification.

A

endochondral

59
Q

the cartilage cells in the condylar head and neck do or do not exhibit ordered columns?

A

do not

60
Q

_____ head of lat pterygoid attaches to the joint capsule and articular disc (a.k.a. meniscus)

A

Superior

61
Q

____ head of lat pterygoid attaches to the condylar neck in the pterygoid fovea

A

Inferior

62
Q

The articulating surfaces are covered with a layer of ___ tissue

A

fibrous tissue

63
Q

Articular surface on the posterior

slope of the articular tubercle.

A

glenoid fossa

64
Q

: Comprised of collagen and elastic fibrous connective tissue, fat cells, and is highly vascular. Elastic fibers from this bilaminar zone insert into the petrotympanic fissure.

A

Retrodiscal Connective Tissue (a.k.a. bilaminar zone)

65
Q

T/F: The disc is attached to the medial
and lateral surfaces of the
condyle, but not the temporal
bone

A

True

66
Q

The most peripheral (external) layer of TMJ synovial membrane is the ____

A

fibrous capsule of the joint

67
Q

The most internal layer of TMJ synovial membrane is the _______

A

intimal layer

68
Q

The intermediate layer of TMJ synovial membrane is the _____

A

vascular subintima

69
Q

The intimal layer contains of what two cell types?

A

Type A and Type b Synovial Cells:

70
Q

Type ___ Synovial Cells:
 Macrophage-like cells that exhibit phagocytic functions
and are capable of producing inflammatory cytokines,
e.g., IL-1, IL-6, IL-8, and TNF-α

A

Type A synovial Cells:

71
Q

Type ___ synovial Cells:
 Fibroblast-like cells that synthesize hyaluronate which
is a major component of the synovial fluid in both the
superior and inferior compartments of the joint.

A

Type B synovial Cells:

72
Q

Chronic or acute joint trauma may cause the Type ____ synovial cells to undergo a syncytial (fusing) transformation into multinucleated giant cells that exhibit osteoclastic-like functions

A

Type A synovial Cells:

73
Q

______: the disc is trapped in the antero-medial position,

causing limited opening, pain, and “clicking” upon opening

A

Internal Derangement:

74
Q

In ____, With these chronic inflammatory changes, osteophytes are noted on the condylar heads. Also, a decreased vascularity is found in the retrodiscal area, leading to pain on function.

A

arthritic degeneration

75
Q

Loss of articular coverings and
synovial membranes, leading to
direct bone-to-bone fusion

A

Ankylosis