SA Endocrinology 6 - Diabetes Mellitus 2

Question 1

What is the mechanism of diabetes mellitus in cats?

Answer 1

Relative insulin insufficiency due to beta-cell dysfunction. Concurrent diseases causing insulin resistance.

Question 2

How can you differentiate stress induced hyperglycaemia with diabetes mellitus?

Answer 2

Fructosamine

Question 3

What is the optimal first choic insulin in cats with diabetes melltius?

Answer 3

Protamine zinc insulin

Question 4

What is the clinical significane in ketone bodies?

Answer 4

Indicate lipolysis (surplus Acetyl CoA as provision of energy substrate at times of Kreb’s cycle failure

Question 5

Whata are the three types of ketones?

Answer 5

Acetone, acetoacetate, betahydroxybutyrate

Question 6

What is the difference between diabete ketotics and diabetes ketoacidotics?

Answer 6

Diabetic ketotics are well patients and treated as per standard DM management.
Diabetic keotacidotics are sikc patietns and treated with neutral insulin and supportive management as needed.