Equine Endocrinopathies Flashcards
What is Equine Cushing’s Disease also known as?
Pituitary Pars Intermedia Dysfunction
What are the 11 main clinical signs of PPID?
Long curly coat
Laminitis
PU/PD
Weight loss
Docile
Neurologic impairment
Hyperhidrosis
Change in fat distribution
Infertility
Skin disease
Peridontal disease
What is the best first line test for equine PPID?
ACTH test
What is the second line test for PPID?
Overnight dexamethasone suppression test (ONDST)
What is the first line test for PPID in a hospital setting?
TRH stimulation test
How long after the first positive test of PPID should you test to recheck dosage and from there on, how often should you test?
Repeat the test in 4-6 weeks to check dose
Repeat annually to see disease progression
What is the main treatment for PPId in horses?
Dopamine agonist - Pergolide
What should you initially do if you suspect thyroid problems in a horse and then what should you do if the result is uncertain?
Measure T4 initially
If result uncertain, TSH stimulation test OR TRH stimulation test
What causes hypothyroidism in foals?
Inadequate or excessive iodine intake by the mare
What is the treatment of hypothyroidism in adults?
Levothyroxine
How should you treat hyperthyroidism in horses?
Anti-thyroid therapy with potassium iodide
What is the most common thyroid tumour in horses and what percenatge of older horses will have this tumour?
Adenoma
30% of aged horses
What is the classic sign of a granulosa-theca cell tumour?
Stallion-like behaviour
What is the best test for a granulosa cell tumour?
Anti-mullerian hormone
