SA Alopecia Flashcards
Alopecia
Hair loss
Causes of sel-induced pruritis.
Pruritic - parasites, allergy
Psychogenic- visceral pain, stress
What is the difference between inflammatory and non-inflammatory alopecia?
Inflammatory leads to damaged follicle
Non-inflammatory leads to hair cycle interruption/ abnormal formation of the hair
Causes of inflammatory alopecia
- Infectious - S. pseudointermedius, dermatophytosis
- Parasitic - Demodecosis, leishmaniasis
- Immune-mediated - alopecia areata, dermatomyositis
What evidence may be suggestive of self-induced alopecia?
Hair in teeth
Vomits hair balls/ hair in faeces
Broken/ frayed hair on trichogram
Short/ spikey hairs
What is the most common cause of bacterial folliculitis in the dog?
Staph. pseudintermedius
Gram +ve coccoi bacterial + neutrophils on cytology (+nuclear streams)

What clinical signs are observed with Staph. pseudintermedius bacterial folliculitis?
Multifocal patches of alopecia
Pustules
Crusts

Ulcerated collarettes

Thick crusts and ulcerated skin

Papules and pustules
What fungal species are associated with Dermatophytosis?
Microsporium canis (gypseum - soil)
Trichophyton mentagrophytes

Fractured hair on trichogram - indicative of self-induced alopecia
What is the difference between a macula and a papule?
Macula are flat, papules are slightly raised - both penetrate deeper tissue (unlike plaques)

Follicular cast on trichogram - indicative of dermatophytosis lesion
Debris, fungal hyphae and arthrospores (soap bubbles)
What clinical signs are indicative of dermatophytosis infection?
Multifocal patches (round) of alopecia
Scaling/ crusts
Hyperpigmentation (chronicity)
Follicular casts
Which species causing dermatophytosis caused greater amounts of inflammation?
Trichophyton
What colour change on DTM is considered positive for Dermatophytosis?
Yellow to red
Dermatophyte test medium

What treatment options are considered for dermatophytosis?
Topical - itraconazole, ketoconazole
Environmental decontamination - 1:10 bleach
Systemic antifungals
Follicular mites
Demodex!
Long-bodied - canis, injai, cati
Short-bodied - cornei, gatoi
What types of patient are more likely to present with demodecosis?
Juveniles - with immature immunesystem
Adults - immunocompromised
Sequelae to demodecosis?
Secondary bacterial infection and folliculitis

Localised patches of demodecosis - mainly seen in juveniles
Alopecia, sclaing, blue-grey pigmentation, comedones, follicular casts

Generalised demodecosis - adult onset demodecosis
Papules, pustules, enlarged LN, painful/ pruritic
Causes non-pruritic alopecia in cats..
Demodex cati
Causes pruritic, infectious demodecosis in cats.
Demodex gatoi
Outline a treatment plan for Demodecosis.
- Anti-mite treatment
- Amitraz (xxx cats), moxidectin, milbemycin, fluralaner, ivermectin
- Clip and remove debris (bathe)
- Treat SBI
- Use treatments until curative

Leishmaniasis
- Alopecia
- Silver scale
- Depigmented
- Nodule, erosions, ulceration, Lymphandenopathy, crusts
- Pyrexia
- Muscle atrophy/ polyarthritis

Amastigotes within macrophages on cytology
Lymphocytic attack on hair follicle
Alopecia areata


Dermatomyositic - causes scaring dermatitis, unknown aetiology
Which endocrinopathies can lead to hair cycle arrest?
- Hyperadrenocorticism
- Hypothyroidism
- Hyperoestrogenism
- Sex hormones?
Alopecia 1-3 months after a stressful event..
Telogen defluxion - leads to synchronous growth
Clinical features of endocrine associated alopecia?
- Bilateral and symmetrical
- Hyperpigmented skin
- Atrophic skin
- Dull/ dry coat
- Poor wound healing
- Post-clipping
Tragic

Myxoedema of the face - secondary to hypothyroidism
Dermatological signs of feminisation due to sertoli cell tumours..
- Testicular discrepancy
- Pendulous prepuce
- Linear preputial erythema
- Gynecomastia


Feline paraneoplastic alopecia
- Pancreatic carcinoma
- Bile duct carcinoma
Skin is shiny and translucent - ventrum and legs
Unknow aetiology of alopecia and hyperpigmentation in plush-coated breeds..

Alopecia X
Found on the trunk

Seasonal flank alopecia - due to change in day length
This breed has congenital alopecia caused by a hair synthesis defect..
Chinese crested
Pattern alopecia
Older age
Minaturisation of hairs
Usually found on pinnae
Lymphocytoc attack of the sebaceous glands
Sebaceous adenitis - greasy hair pluck