S9 L1 GI Emergencies Flashcards

1
Q

What is the key feature of peritonitis?

A
  • Diffuse abdominal pain that will be sudden if perforated viscus
  • Patient will often lie very still and any movement is very painful. Shallow breathing and flexed knees
  • Control the infectious source, eliminate bacteria and support organs
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2
Q

What is the difference between primary and secondary peritonitis?

A

Primary: spontaneous infection of ascitic fluid. vomiting, abdominal pain and fever

Secondary: results from inflammatory process leading to perforation or gangrene of abdominal viscera, e.g appendicitis, peptic ulcer disease, ovarian cyst, tubal pregnancy

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3
Q

How does a cirrhotic liver lead to ascites?

A
  • Portal hypertension increases hydrostatic pressure in the veins draining the gut
  • Decreased liver function so less albumin production so lower oncotic pressure holding in fluid
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4
Q

What are the common causes of bowel obstruction?

A

Adults: post op adhesions, incarcerated hernias

Children: intussusception, intestinal atreisa, meconium ileus

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5
Q

What is intussusception, how does it cause bowel obstruction and how do you treat it?

A
  • One segment of the bowel telescopes into the other, usually due to a mass like an enlarged lymph node or Meckel’s diverticulum
  • Lymphatic and venous drainage can be impaired and you get oedema and infarction
  • Abdominal pain, vomiting, haematochezia
  • Air enema or surgery
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6
Q

What is the common presentation of small bowel obstruction?

A
  • Start sudddenly with peri-umbilical pain, nausea and vomiting
  • Abdomen tender and distended
  • High pitched bowel sounds
  • Late absolute constipation
  • Usually due to abdominal adhesions
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7
Q

How can we diagnose a small bowel obstruction?

A

- History of abdominal pain

- Physical examination: high pitched bowel sounds, presence of hernia, abdominal distension

- Image with x-ray to see distended loops

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8
Q

What is the common causes of large bowel obstruction?

A

- Colorectal cancer

  • Volvulus
  • Strictures from diverticulitis

Most occur distal to splenic flexure

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9
Q

What are some common symptoms of large bowel obstruction?

A
  • Periumbilical or suprapubic pain
  • Abdominal distension and pain
  • Nausea/vomiting
  • Constipation then diarrhoea
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10
Q

Where are the most common areas for a volvulus to occur?

A
  • Caecum
  • Sigmoid

Overloaded sigmoid from constipation can twist on its axis

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11
Q

What are the differences between small and large bowel obstruction?

A
  • Small bowel tends to be younger age group than large
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12
Q

Who is more at risk of acute mesenteric ischaemia and what can it be caused by?

A
  • More common in females, elderly and peripheral vascular disease

Caused by:

  • Emboli in SMA
  • Arterial or venous thrombosis
  • Vasculitis
  • Vasoconstriction
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13
Q

How does acute mesenteric ischaemia present?

A
  • Difficult to detect
  • Abdominal pain disproportionate to clinical findings

- Fever, diarrhoea, nausea and haematochezia

  • Pain often left sided as splenic flexure is fragile
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14
Q

How would you investigate and treat a suspected acute mesenteric ischaemia?

A
  • Blood test for metabolic acidosis/increased lactate levels
  • Erect CXR for perforation

- CT angiography

  • Surgery to resect ischaemic bowel
  • Surgical embolectomy
  • Thrombolytic agents
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15
Q

What are the common causes for upper GI bleeding?

A
  • Peptic ulcers (gastric antrum/lesser curve > duodenal)
  • Varices

Most upper GI bleeds stop spontaneously

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16
Q

What is the main cause of oesophageal varices?

A
  • Portal hypertension
  • 90% of people with this will develop varices and 30% of these will bleed
17
Q

How can we treat upper GI bleeding?

A

Variceal: vasopressin agonist called terlipressen that reduces portal vein pressure

Other: endoscopy with clips, coagulation/thrombin. PPIs are given after

18
Q

If we cannot control oesophageal varices bleeds by band ligation or terlipressin, what else can we do to intervene?

A

Bypasses the liver

19
Q

What is the definition of an AAA?

A

Dilation of the aorta up to 1.5 times expected, usually over 3cm in diameter (infrarenal aorta should be 1.5cm)

Due to a breakdown of the media in the arterial wall

20
Q

What are the risk factors for an AAA?

A
  • Male
  • Over 65
  • Smoke
  • Peripheral atherosclerotic disease

Most are asymptomatic and found incidentally

21
Q

What are the symptoms of an AAA about to rupture?

A
  • Back and abdominal pain
  • Pulsatile mass in abdomen
  • Signs of cardiovascular collapse, e.g syncope, transient hypotension
22
Q

How do you diagnose an AAA?

A
  • Physical examination
  • Ultrasonography
  • CT
  • Plain x-rays as aneurysm may have calcified
23
Q

How do you treat an AAA?

A

Unruptured: endovascular stent graft, smoking cessation, surveillance

Ruptured: emergency resuscitation, clamp the aorta and suture in a synthetic graft

24
Q

Why does a patient have a normal blood pressure when their aorta initially ruptures?

A

Aorta is in the retroperitoneum which is a small space so the blood has a tamponade effect at first

25
Q

How does C.Diff cause diarrhoea and why is it such an issue in hospitals?

A
  • Toxin A (enterotoxin stimulating fluid secretion) and toxin B (cytotoxin)
  • Spores, need a deep cleaning, doesn’t wash off with alcohol gel
  • Need to isolate patients, give them fluid and oral metronidazole and stop any other antibiotics
26
Q

At what vertebral level is this CT taken?

A

T12 - can see the coeliac trunk!

27
Q

What type of hernia might be precipitated by a weakened conjoint tendon?

A

Direct

28
Q

Which branch of the Coeliac trunk (Labelled CT) supplies blood to the lesser curve of the stomach?

A
  • Left gastric
  • Look for Mercedes sign
29
Q

Where is the hepato-renal recess?

A
  • Betweent the inferior surface of the liver and the kidney
  • Shouldn’t normally be filled with fluid
30
Q

How can you tell where the caudate lobe is on the inferior view of the liver?

A
  • GQ magazine so quadrate next to gallbladder so caudate is the other one
31
Q

Which part of the stomach has the highest density of G cells?

A
32
Q

What structures lie in the free edge of the lesser omentum?

A
  • Hepatic artery
  • Hepatic portal vein
  • Common bile duct
33
Q

What are the boundaries of the lesser sac?

A

Anterior: lesser omentum and posterior stomach

Posterior: pancreas

(google rest)

34
Q

What separates the supra and infracolic compartments?

A

Transverse mesocolon

35
Q

GW:

  • Which area of the GI tract does Crohn’s usually start?
  • Most common extra-interstinal probelms associated with IBD?
  • What causes the cobblestone appearance in Crohn’s?
  • What histological features might you see on a biopsy of the gut wall taken from a patient with Ulcerative colitis?
  • Explain why CT and MRI scans are less useful for investigating UC compared to Crohn’s?
A
  • Terminal ileum
  • Joint pain - Arthritis
  • Muscosal oedema (‘middle bits’), surrounded by ulcers
  • Absess in crypts, crypt distortion. Chronic inflammatory infiltrate in lamina propria. Darker, crowded nuclei. Exudate in lamina propria
  • Crohn’s has more obvious changes on CT and MRI, e.g. strictures, fistulas UC - changes purely on mucosa, not as obvious - investigate via colonoscopy
36
Q

GW:

  • Explain why osmotic diarrhoea improves when you stop eating but secretory diarrhoea continues?
  • Explain why (referencing the anatomy of the appendix) Appendicitis can present differently in different people
  • Briefly describe the factors that collectively enable us to be continent with regard to faeces
  • Explain why tenesmus is potentially a red flag symptom?
  • Explain why the pain associated with (classic) Appendicitis moves location in the abdomen as the disease process develops?
  • Explain why you get pain with external haemorrhoids but not with internal haemorrhoids?
A
  • Osmotic - gut lumen contents, pulls water in e.g. lactose intolerance, anything stopping you from absorbing Secretory - affecting the pump (issue with epithelium), infective cause
  • Appendix position is different in different people. E.g. in people with pelvic and retro-cecal - may not get right iliac fossa pain, as when enlarged, it doesn’t come in contact with parietal peritoneum (or take longer to get the pain)
  • Internal and external feaces, Firm, bulky faeces, Distension of rectum, Anal cushion, Puborectalis, Normal anal-rectal angle
  • Mass in the rectum (same effect as if feaces was there…). Feeling of not fully evacuating the bowels - feeling of fullness could be caused by a mass
  • Inflammatory:
    • Visceral afferent neurones - Beginning - gets T10 (where the visceral afferents come in from the appendix)
    • More inflammed - ends up hitting the parietal peritoneum (somatic nerves innervate this), then more localised pain to the position of the appendix
  • External haemorrhoids - below dentate line, somatic nerves Internal haemorrhoids - above dentate line, visceral afferent (splanchnic nerves)