S8 L1 Upper GI Malignancy

Question 1

GI Malignancy prevalance
- Which cancers most common?

Reminder: Type of cancer linking to epithelium…

• Stratified squamous…
• Columnar epithelium…

Answer 1

GI malignancy prevalence:
Really common: Bowel cancer is the third most common cancer
affecting men and women
Pancreatic, stomach, oesophageal, liver cancer - all feature in top
20 common cancers

Links to Epithelium
Stratified squamous = squamous cell carcinoma
Columnar epithelium = Adenocarcinoma

Question 2

Upper GI Malignancy:
- 3 most common symptoms (and the ‘main’ cancer associated with each)

Answer 2

• Dysphagia (oesophageal)
• Epigastric pain (gastric)
• Jaundice (liver, pancreatic, bile duct)

Question 3

1st Main Symptom: Dysphagia

• Occurs due to…
• Key feature of the dysphagia…
• Red Flags for the dysphagia

Answer 3

Question 4

Oesophagus cancer names:
- Type of cancer…

For the ‘main’ one… (A___):

• Risk factors
• Identifying this cancer?
• Survival rate?

Answer 4

Question 5

2nd Main Symptom:
Epigastric pain
- Causes of this pain (some differentials)
- Red flags for Epigastric pain
- Causes of haematemesis (some differentials)

Answer 5

Question 6

Gastric cancer
- 3 main types

Answer 6

Question 7

Gastric Adenocarcinomas:

• Risk factors
• Investigations
• Symptoms
• Prognosis
• Screening

Answer 7

Question 8

3rd Main Symptom: Jaundice

• Red flags accompanying this
• Main cancers associated with jaundice and the red flags

Answer 8

Question 9

Pancreatic cancer

• Type of cancer…
• Which of the 3 main symptoms if most likely? (think about location of the mass)
• Risk
• Prognosis

Answer 9

Question 10

Cancer of the bile ducts

• Name
• Prognosis
• Risks

Answer 10