S8 Peripheral Arterial and Venous Disease Flashcards

1
Q

What is the lower limb venous system divided into?

A
  • superficial veins - in the subcutaneous fat

* deep veins - underneath the deep fascia, with major arteries

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2
Q

In which direction does blood move in respect to superficial and deep veins?

A

Moves superficial to deep

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3
Q

What are the superficial veins in the lower limbs?

A
  • short saphenous vein
  • long saphenous vein
  • tributaries of the long saphenous vein)
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4
Q

What are the deep veins of the lower limbs?

A
  • inferior vena cava
  • common iliac
  • external iliac
  • common femoral
  • deep femoral
  • superficial femoral
  • popliteal
  • anterior tibial
  • posterior tibial
  • peroneal
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5
Q

What is the calf muscle pump?

A

The soleus and gastrocnemius contribute to pushing blood against gravity back towards the heart

So venous pressure in the foot is reduced during exercise

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6
Q

What are varicose veins? What is the most common site of this pathology?

A

When the valves are ineffective and blood movement is slow/reversed - veins are twisted. No problems but can be symptomatic .

Saphenous veins

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7
Q

How do varicose veins develop?

A
  1. Walls of the veins weaken

2. Leading to development of varicosities and the valve cusps separate - become incompetent

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8
Q

What symptoms does someone with varicose veins have?

A
  • heaviness
  • aching
  • muscle cramps
  • throbbing
  • varicose eczema
  • superficial vein thrombophlebitis
  • painful erythema
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9
Q

What is someone with varicose veins at increased risk of developing?

A

DVT

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10
Q

What is chronic venous insufficiency?

A

When the venous wall and valves in leg aren’t working effectively - so difficult to return blood back to heart - causes pooling of blood (stasis) which leads to venous hypertension oedema

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11
Q

What can chronic venous insufficiency lead to?

A
  • haemosiderin staining
  • lipodermatosclerosis
  • venous ulceration
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12
Q

What is lipodermatosclerosis?

A

Inflammation and thickening of fat layer under skin

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13
Q

What can venous eczema lead to?

A

Lipodermatosclerosis - hard to the touch

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14
Q

What does venous eczema present as?

A

Chronic, itchy red, swollen and tight skin

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15
Q

What does venous ulceration present as? Where does it usually occur?

A

Chronic and painful

Usually occurs around hard modular areas like the medial malleolus

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16
Q

When does the calf muscle pump fail?

A

When not using the calf muscle properly - not doing plantarflexion of ankle joint during walking

17
Q

Who’s at risk of calf muscle pump failure?

A

Those who are (more) immobile - injured, post/pre-op patients, elderly, obese

And people with Parkinson’s disease - no plantarflexion of ankle joint

18
Q

How do you treat ulceration?

A

Ligation and vein stripping

19
Q

What is the main cause of arterial thrombosis?

A

Atheroma as arteries are platelet rich

20
Q

What is the main cause of venous thrombosis?

A
Stasis and another factor 
E.g.
* dehydration
* trauma 
* chemotherapy 
* inflammatory conditions 
* pregnancy
21
Q

What is DVT? What response does it lead to?

A

Clotting of blood in a deep vein (usually the calf) due to impaired venous return and hypercoagulability

Leads to an inflammatory response - pain, swelling, redness

22
Q

When is stasis e.g. no calf pump muscle likely? What is it good to do in response?

A
  • before surgery
  • after surgery
  • trauma
  • malignancy
  • pregnancy

Promote mobility soon after surgery

23
Q

What is usual treatment/prophylaxis for DVT?

A

Anticoagulant agents

24
Q

What is the fatal consequence of a DVT?

A

Pulmonary embolism

25
What prevents acute ischaemia when we flex/bend a joint?
Collateral circulation
26
What is our adaptive response to stenosis of a major vessel over a long period?
Collateral circulation
27
When doesn’t collateral circulation develop in ischaemia? What are some examples of this?
When the occlusion is acute - happens in minutes-days Trauma and embolism e.g. atrial fibrillation, popliteal artery aneurysm, sudden rupture of atherosclerotic plaque
28
What are the 6 Ps of leg ischaemia?
* pain * pallor * perishing with cold * pulseless * paraesthesia * paralysis or reduce power Pallor, paraesthesia and paralysis could be subtle
29
How does chronic peripheral arterial disease present?
* intermittent claudication - exercise induced | * pain goes away upon rest
30
How do you manage chronic peripheral arterial disease?
Exercise, smoking cessation, antiplatelet drugs, angioplasty, bypass graft
31
What is critical ischaemia? What occurs if left untreated?
Pain at rest (due to v poor blood supply) Ulceration and gangrene
32
What is the most common presentation of claudication? What occurs if left untreated?
Atheroma (atherosclerosis of superficial femoral artery - present with calf claudication) Leads to critical ischaemia
33
What lower limb pulses can be palpated?
* femoral pulse (mid-inguinal point) * dorsal is pedis pulse (lateral to extensor hallucis longus tendon) * popliteal pulse (deep in popliteal fossa) * posterior tibial pulse (behind the medial malleolus)
34
What can you use to measure realtime flow and velocity of blood?
Ultrasound and the Doppler effect
35
What is the ankle-brachial pressure index (ABPI)?
Divide the ankle systolic pressure by the brachial systolic pressure An ABPI of less than 0.9 indicates peripheral artery disease
36
How is Doppler ultrasonography used in distal blood vessels?
Used in legs when diagnosing peripheral arterial disease e.g. Atheroma, stenosis, means flow and velocity changes