Rubin's Viruses Flashcards

1
Q

2 major causes of the common cold?

A

rhinovirus, coronavirus

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2
Q

“rhinorrhea + pharyncgitis + cough + low grade fever”

A

common cold

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3
Q

Genome of rhinovirus, coronavirus, influenza?

A

RNA virus

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4
Q

“rapid onset fever + chills/ myalgias + HA + nonproductive cough”

A

influenza

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5
Q

What causes croup?

A

parainfluenza

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6
Q

Classic symptom of croup?

A

“barking cough”, inspiratory stridor

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7
Q

Cause of bronchiolitis in infants?

A

RSV

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8
Q

“diffuse alveolar damage with multinucealted syncitial cells without viral inclusions”

A

SARS

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9
Q

What is the cause of the rash in measles?

A

T cells on virally infected vascular epithelium

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10
Q

“koplik spots (dew drop on rose pedals) that begin on face then spread to rest of body”

A

measles

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11
Q

“fever + rhinorrhea + conjunctivitis + mucosal/ skin lesions”

A

measles

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12
Q

Congenital abnormalities associated with rubella?

A

deafness, cataracts, glaucoma, heart defects and mental retardation

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13
Q

“parotid gland swelling and meningoencephalitis”

A

mumps

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14
Q

Vector for yellow fever?

A

Aedes mosquito

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15
Q

Damage in yellow fever?

A

extensive hepatic necrosis and jaundice

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16
Q

most widespread destructive hemorrhagic fever?

A

Ebola

17
Q

“rash + lymphadenopathy + polyarthropathy”

A

west nile virus

18
Q

Common cause of ARD and pneumonia in military recruits?

A

Adenovirus

19
Q

Cause of “fifth disease”/ erythemia infectiosum?

A

Human Parvovirus B19

20
Q

What occurs in B19 infection in people with hemolytic anemia?

A

Transient aplastic crisis

21
Q

Cause of smallpox?

A

variola virus

22
Q

How does VZV spread?

A

respiratory route and contact with skin lesions

23
Q

Where does VZV establish latency?

A

DRG

24
Q

Descrive the rash in VZV?

A

Pruritic rash that starts on head then spreads to truncks and extremities

25
Q

Which HSV is associated with encephalitis?

A

HSV1

26
Q

Which HSV is associated with meningitis?

A

HSV2

27
Q

“Fever + Pharyngitis + LAD + increased lymphocytes + splenomegaly”

A

EBV

28
Q

Reed Sternberg cells are associated with which viral infection?

A

EBV

29
Q

Where does EBV establish latency?

A

B cells

30
Q

Where does CMV establish latency?

A

WBC

31
Q

Which herpes virus is assocaited with a lot of congenital infections?

A

CMV

32
Q

Which virus causes proliferative lesions of squamous epithelium?

A

HPV

33
Q

What is kiolocytosis?

A

large squamous cells with shrunken muceli enveloped in large cytoplasmic vavules (Kiolocytes)

34
Q

What is verruca vulgaris?

A

common wart

35
Q

What is condyloma acuminatum?

A

soft, raised, fleshy lesions on the penis, vulva vaginal wall, cervix or perianular region