Rubin's Viruses Flashcards

1
Q

2 major causes of the common cold?

A

rhinovirus, coronavirus

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2
Q

“rhinorrhea + pharyncgitis + cough + low grade fever”

A

common cold

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3
Q

Genome of rhinovirus, coronavirus, influenza?

A

RNA virus

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4
Q

“rapid onset fever + chills/ myalgias + HA + nonproductive cough”

A

influenza

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5
Q

What causes croup?

A

parainfluenza

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6
Q

Classic symptom of croup?

A

“barking cough”, inspiratory stridor

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7
Q

Cause of bronchiolitis in infants?

A

RSV

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8
Q

“diffuse alveolar damage with multinucealted syncitial cells without viral inclusions”

A

SARS

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9
Q

What is the cause of the rash in measles?

A

T cells on virally infected vascular epithelium

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10
Q

“koplik spots (dew drop on rose pedals) that begin on face then spread to rest of body”

A

measles

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11
Q

“fever + rhinorrhea + conjunctivitis + mucosal/ skin lesions”

A

measles

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12
Q

Congenital abnormalities associated with rubella?

A

deafness, cataracts, glaucoma, heart defects and mental retardation

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13
Q

“parotid gland swelling and meningoencephalitis”

A

mumps

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14
Q

Vector for yellow fever?

A

Aedes mosquito

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15
Q

Damage in yellow fever?

A

extensive hepatic necrosis and jaundice

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16
Q

most widespread destructive hemorrhagic fever?

17
Q

“rash + lymphadenopathy + polyarthropathy”

A

west nile virus

18
Q

Common cause of ARD and pneumonia in military recruits?

A

Adenovirus

19
Q

Cause of “fifth disease”/ erythemia infectiosum?

A

Human Parvovirus B19

20
Q

What occurs in B19 infection in people with hemolytic anemia?

A

Transient aplastic crisis

21
Q

Cause of smallpox?

A

variola virus

22
Q

How does VZV spread?

A

respiratory route and contact with skin lesions

23
Q

Where does VZV establish latency?

24
Q

Descrive the rash in VZV?

A

Pruritic rash that starts on head then spreads to truncks and extremities

25
Which HSV is associated with encephalitis?
HSV1
26
Which HSV is associated with meningitis?
HSV2
27
"Fever + Pharyngitis + LAD + increased lymphocytes + splenomegaly"
EBV
28
Reed Sternberg cells are associated with which viral infection?
EBV
29
Where does EBV establish latency?
B cells
30
Where does CMV establish latency?
WBC
31
Which herpes virus is assocaited with a lot of congenital infections?
CMV
32
Which virus causes proliferative lesions of squamous epithelium?
HPV
33
What is kiolocytosis?
large squamous cells with shrunken muceli enveloped in large cytoplasmic vavules (Kiolocytes)
34
What is verruca vulgaris?
common wart
35
What is condyloma acuminatum?
soft, raised, fleshy lesions on the penis, vulva vaginal wall, cervix or perianular region