Rubin's Viruses Flashcards
2 major causes of the common cold?
rhinovirus, coronavirus
“rhinorrhea + pharyncgitis + cough + low grade fever”
common cold
Genome of rhinovirus, coronavirus, influenza?
RNA virus
“rapid onset fever + chills/ myalgias + HA + nonproductive cough”
influenza
What causes croup?
parainfluenza
Classic symptom of croup?
“barking cough”, inspiratory stridor
Cause of bronchiolitis in infants?
RSV
“diffuse alveolar damage with multinucealted syncitial cells without viral inclusions”
SARS
What is the cause of the rash in measles?
T cells on virally infected vascular epithelium
“koplik spots (dew drop on rose pedals) that begin on face then spread to rest of body”
measles
“fever + rhinorrhea + conjunctivitis + mucosal/ skin lesions”
measles
Congenital abnormalities associated with rubella?
deafness, cataracts, glaucoma, heart defects and mental retardation
“parotid gland swelling and meningoencephalitis”
mumps
Vector for yellow fever?
Aedes mosquito
Damage in yellow fever?
extensive hepatic necrosis and jaundice
most widespread destructive hemorrhagic fever?
Ebola
“rash + lymphadenopathy + polyarthropathy”
west nile virus
Common cause of ARD and pneumonia in military recruits?
Adenovirus
Cause of “fifth disease”/ erythemia infectiosum?
Human Parvovirus B19
What occurs in B19 infection in people with hemolytic anemia?
Transient aplastic crisis
Cause of smallpox?
variola virus
How does VZV spread?
respiratory route and contact with skin lesions
Where does VZV establish latency?
DRG
Descrive the rash in VZV?
Pruritic rash that starts on head then spreads to truncks and extremities
Which HSV is associated with encephalitis?
HSV1
Which HSV is associated with meningitis?
HSV2
“Fever + Pharyngitis + LAD + increased lymphocytes + splenomegaly”
EBV
Reed Sternberg cells are associated with which viral infection?
EBV
Where does EBV establish latency?
B cells
Where does CMV establish latency?
WBC
Which herpes virus is assocaited with a lot of congenital infections?
CMV
Which virus causes proliferative lesions of squamous epithelium?
HPV
What is kiolocytosis?
large squamous cells with shrunken muceli enveloped in large cytoplasmic vavules (Kiolocytes)
What is verruca vulgaris?
common wart
What is condyloma acuminatum?
soft, raised, fleshy lesions on the penis, vulva vaginal wall, cervix or perianular region
