Rubin's Stomach Flashcards
What do chief cells secrete?
pepsin, gastric lipase
What do parietal cells secrete?
HCl, intrinsic factor
What do G cells secrete? D cells?
G= gastrin
D= somatostatin
“congenital malformation of the anterior abd wall leading to exposure of abdominal contents”
Gastroschisis
“Persistent herniation of bowel into umbilical cord”
Omphalocele
“congenital hypertrophy of pyloric smooth muscle that is more common in males”
Pyloric stenosis
Symptoms of pyloric stenosis?
Projectile vomiting, visible peristalsis, olive like mass in the abdomen
“acidic damage to the stomach mucosa due to imbalance between mucosal defenses and acidic environment”
Acute gastritis
Who are curling ulcers seen in?
severely burned patients
Who are cushing ulcers seen in?
people with CNS trauma and increased ICP
What causes ulcers in patients that use NSAIDS?
decreased PGE2
“chronic inflammation of stomach mucosa”
chronic gastritis
Most common cause of chronic gastritis in the US?
H. pylori infection
H pylori increases cancer risk for which type of canver?
MALT lymphoma
What characterizes atrophic gastritis?
chronic inflammation, lymphoid follicles, gland degeneration, and intestinal metaplasia
Where in the stomach does chronic autoimmune gastritis affect?
body and fundus
Where in the stomach does H. pylori gastritis affect?
antrum
Villiform projections and increased smooth muscle are seen with which type of chronic gastritis?
reactive gastritis
“hyperplastic hypersecretory gastropathy with elongated glands lined by mucus secreting epithelial cells”
Menetrier disease
Adult and childhood causes of menetrier disease?
Child= CMV
Adult= TGF alpha overexpression
“focal destruction of gastric mucosa and small intestine caused by gastric secretions”
peptic ulcer disease
Risk factors for peptic ulcer disease?
HCl secretion and H. pylori infection, drugs, cigarette smoking, rapid gastric emptying
Duodenal ulcers are almost always due to…
H. pylori
Describe the pain with duodenal ulcers?
epigastric pain that IMPROVES with meals
