RSI Medications

Question 1

What is the RSI dose for Pancuronium?

Answer 1

Pancuronium (Pavulon)
Non-Depolarizing Neuromuscular Blocking Agent

0. 1 mg/kg IVP (Induction Dose)
1. 01 mg/kg (Long-Term Paralysis Dose)

Onset: 120 - 300 seconds ; Duration: 120 - 150 mins

Question 2

What is the RSI dose for Propofol?

Answer 2

Propofol - Diprivan - Induction Agent

1.5 - 3.0 mg/kg IVP

Onset: 15 - 45 seconds ; Duration: SHORT

** Mean duration of bolus dose 2 - 2.5 mg/kg is approx. 3 - 5 minutes **

Question 3

What is the RSI dose for Ketamine?

Answer 3

Ketamine (Ketalar) - Induction Agent

2 mg/kg IVP

Onset: 30 - 45 seconds ; Duration: 10 - 20 mins

Question 4

What the the preferred non-depolarizing neuromuscular blocking agents utilized for RSI?

Answer 4

Vecuronium (Norcuron) - 0.1 - 0.15 mg/kg

Pancuronium (Pavulon) - 0.1 mg/kg IVP (Induction)
- 0.01 mg/kg (paralysis)

Rocuronium (Zemuron) - 1 mg/kg

Question 5

What is the RSI dose for Rocuronium?

Answer 5

Rocuronium (Zemuron) -
Non-Depolarizing Neuromuscular Blocking Agent

1 mg/kg

Onset: 60 - 90 seconds ; Duration: 30 - 100 mins

Question 6

Which depolarizing medication is commonly used in the EMS/Prehospital environment?

Answer 6

Succinylcholine (Anectine) -
Depolarizing Neuromuscular Blocking Agent

** only depolarizing agent used by EMS **

Adult: 1 - 2 mg/kg IV/IO
3 - 4 mg/kg IM

Child: 2 mg/kg IVP

Newborn (< 12 months):
3 mg/kg IVP

Question 7

What are some special considerations while using Midazolam for RSI?

Answer 7

1. Variable response
2. Hypotension
3. Apnea at high doses
4. Caution in elderly, renal patients

Question 8

What is the RSI dose for Midazolam?

Answer 8

Midazolam (Versed) - Induction Agent

0.2 - 0.3 mg/kg IVP

Onset: 30 - 60 seconds ; Duration: 15 - 30 mins

Question 9

What is the RSI dose for Etomidate?

Answer 9

Etomidate (Amidate) - Induction Agent

0.3 mg/kg IV/IO

Onset: 15 - 45 seconds ; Duration: 3 - 12 mins

Question 10

What is the RSI dose for Succinylcholine?

Answer 10

Succinylcholine (Anectine) -
Depolarizing Neuromuscular Blocking Agent

Adult: 1 - 2 mg/kg IV/IO
3 - 4 mg/kg IM

Child: 2 mg/kg IVP

Newborn (< 12 months):
3 mg/kg IVP

Question 11

What is the RSI dose for Vecuronium?

Answer 11

Vecuronium (Norcuron)
Non-Depolarizing Neuromuscular Blocking Agent

0. 1 - 0.15 mg/kg (Paralysis Dose)
1. 3 - 0.4 mg/kg (Induction Dose)

Onset: 90 - 120 seconds ; Duration: 35 - 60 mins