Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Block 6 Week 4 Colt > +/- RNA viruses - AuCoin > Flashcards

+/- RNA viruses - AuCoin Flashcards

1
Q

Describe the genome of reo virus?

A

segmented dsRNA

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

how is reovirus transmitted?

A

fecal oral route

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

What is the most common cause of severe diarrhea in INFANTS?

A

REOVIRUS

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Where does reovirus replicate?

A

mucosal cells of the small intestine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

where is the specific strain of reovirus that is infectious?

A

rotavirus

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

T/f: rotavirus diarrhea is bloody

A

false

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

HOw do you diagnose rotavirus?

A

clinical, can use ELISA on stool samples

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

what is the Tx for rotavirus?

A

oral rehydration therapy to replace lost electrolytes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

What are the two vaccines available for rotavirus?

A

Rotarix and Rota Teq

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

T/f: the +RNA strand of dsRNA is directly translated into protein

A

false

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Describe the process of producing mRNA from dsRNA?

A

genomic -RNA is made into mRNA (+sense)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

T/F: dsRNA must have a physical RNA dep RNA pol wihtin the capsid to be infectious

A

true

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

does the segmented RNA genome of rotavirus code for polyproteins or for one-protein-one gene?

A

one protein one gene

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

What is unique about the post translational mod of the rotaviral mRNA?

A

it is capped but lacks a poly A tail

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

What cellular structure is required for rotaviral uncoating?

A

low pH of the lysosome

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

where in the world are deaths from rotavirus common?

A

afrika

17
Q

what do both of the rotavirus vaccines contain?

A

live attenuated virus

18
Q

Human T-lymphotropic virus is an oncovirus associated with (blank)

A

adult T-cell leukemia

19
Q

What cell does HTLV infect?

A

CD4+ T cells

20
Q

How is HTLV transmitted?

A

in semen, blood, and breast milk

21
Q

ATL has a loooooong incubation period of:

A

20-50 years

22
Q

What are the hallmarks of ATL?

A

increased skin lesions, leukemia cells, hepatosplenomegaly, and hypercalcemia

23
Q

How do you diagnose HTLV?

A

ELISA serology

24
Q

Is there a vaccine for HTLV?

A

No, or we would have a cure for cancer!!

25
Q

In HIV, (blank) binds the CD4 receptor

A

gp120

26
Q

to what cells does gp120 bind?

A

T cells, monocytes, and dendritic cells

27
Q

What are the ways that HIV is transmitted?

A

sex, blood, IVDU, and vertically

28
Q

What word do we use to describe the types of infections that HIV patients get?

A

opportunistic

29
Q

The acute phase of HIV infection has what types of symptoms?

A

flu like

30
Q

latent HIV infection has what symptoms?

A

weight loss, night sweats, fatigue, lymphadenopathy

31
Q

How long does it take for HIV to go to AIDS?

A

10 years

32
Q

What is the threshold for AIDS diagnosis?

A

less than 200 T cells/ml

33
Q

How do you diagnose HIV?

A

serology, then RT PCR to determine viral load

34
Q

Oral thrush could be a sign in context that a patient has?

A

HIV

Block 6 Week 4 Colt (10 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions