Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Block 6 Week 4 Colt > + RNA NON-enveloped viruses - AuCoin > Flashcards

+ RNA NON-enveloped viruses - AuCoin Flashcards

1
Q

Are picornaviruses naked or encapsulated?

A

naked

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

what is the shape of the picornavirus capsule??

A

icosahedral

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

What type of nucleic acid is used in the picornavirus? ss or ds?

A

ssRNA

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

what sense is the ssRNA picornavirus?

A

+ sense

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Enteroviruses are resistant to what range of pH?

A

3-9

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Rhinovirus are labile at (acidic/basic) pH

A

acidic

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

What is the optimum growth temp for rhinovirus?

A

33°C

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

T/F: enteroviruses can survive in sewage, detergents, and high heat

A

true

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

T/F: picornaviruses are still infectious without their capsid

A

true

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Where do picornaviruses replicated?

A

cytosol

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Do picornaviruses use the one-gene-one protein model or a polyprotein?

A

polyprotein

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

What are the three major families within picornavirus?

A

Enterovirus
Rhinovirus
Heparnavirus

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

What are the enteroviruses?

A
  1. poliovirus
  2. Coxsackie A and B
  3. Echovirus
  4. Enterovirus
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

What is the ONE virus within rihinovirus?

A

rhinovirus

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

What is the ONE virus within heparnavirus?

A

Hep A virus

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Is the RNA-dep RNA Pol necessarily present in the capsid?

A

No, it is coded by the + RNA genome

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

Is the picornavirus capsid endocytosed?

A

No, the genome is INJECTED

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

what sense RNA is made from the picronavirus genome?

A

-RNA as a template

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

Is the VPg primer attached to the +RNA or -RNA duplicate?

A

+RNA

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

What is the mode of transmission of enterovirus?

A

fecal oral

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

only (blank)% of enterovirus infections are clinically apparent

A

1%

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

Where is the site of initial rep of enterovirus?

A

oropharynx and small intestine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

What are the symptoms caused by the initial rep of enterovirus? (think of where they rep!)

A

nausea and vomiting

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
24
Q

Poliomyelitis is an acute infection of the (blank) and the motor neurons of the spinal cord and brain stem

A

meninges

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
25
The Salk and Sabin vaccines are used for(blank)
polio
26
Where is polio still ENDEMIC?
Nigeria, Pakistan, and Afghanistan
27
How do you Dx polio?
Acute onset of flaccid paralysis, or recovery of poliovirus from stool sample or swab of pharynx
28
How many polio serotypes are there?
three
29
T/F: protection from one polio serotype will protect against them all
FALSE; little immune cross reactivity, therefore you need unique Abs to all three
30
Which polio vaccine is the killed vaccine?
Salk (inactivated vaccine)
31
Which polio vaccine is the live attenuated vaccine?
Sabin, ORAL vaccine
32
T/F: ENTEROvirus can cause viral meningitis
true!
33
when are most viral meningitis cases diagnosed?
summer
34
What age group normally gets enteroviral meningitis?
kids younger than 5
35
What the common "real-world" actions that spread enteroviral meningitis?
changing the diaper or using the toilet and not properly washing hands after
36
What are the symptoms of viral meningitis?
sudden onset of fever, headache, and stiff neck
37
What are the symptoms that are secondary to the meningitis triad?
nausea/vomiting photophobia altered mental status
38
How long does viral meningitis normally last?
7-10 days
39
T/F: Immunocompetent patients are still at risk of dying from viral meningitis
false; they normally recover :)
40
What samples do you take to test for viral meningitis?
blood or CSF
41
What other viruses besides enterovirus can lead to viral meningitis?
mumps, herpesvirus (EBV, HSV, VZV), measles, and influenza
42
What age group does Coxsackie normally infect?
young people
43
Hand foot mouth disease is Coxsackie group (A/B)
Group A
44
What is the clinical word for hand foot mouth disease? What are the actual symptoms?
Herpangia; ulcers in oropharynx, fever, sore throat
45
What is the clinical word to describe Coxsackie B? what are the symptoms?
pleurodynia: fever and severe pleuritic chest pain myocarditis: fever, chest pain, signs of heart failure
46
T/F: both Coxsackie groups can cause asceptic meningitis and mild paralysis
true
47
How do you diagnose Coxsackie infections?
PCR of enteroviral RNA in CSF!!!
48
Is there treatment for coxsackie infection?
nope
49
THe pleurodynia is pain a (plueritis/myositis)
myositis; infection the intercostal muscles and not actually the pleura
50
What does ECHOvirus stand for?
enteric cytopathic human orphan
51
How are echovirus transmitted?
fecal oral
52
Pool water often carries strains of (blank)
echovirus
53
Coxsackie and (blank) virus are leading causes of asceptic meningitis
echovirus
54
What is different about the Rhinovirus capsule from the other picornavirus capsules?
its is an ACID LABILE naked capsid
55
What is the main cause of the common cold?
rhinovirus
56
What is the portal of entry of rhinovirus?
URT
57
what is the ideal temp for rhinovirus rep? what does this mean about where it will infect?
33C, will stay in the nose rather than go into the lung
58
What is the incubation period of rhinovirus
2-4 days
59
T/F: rhinovirus presents with fever and aches
false; normally absent
60
Because rhinovirus is acid labile, it cannot infect what mucsoal tract?
GI tract
61
What is the numericla name for Hep A virus?
enterovirus 72
62
What is the mode of transmission of Hep A?
fecally contaminated food or water
63
Jaundice, DARK urine, PALE feces, elevated AST/ALT, fatigue, fever, N/V are characteristic of?
Hep A infection
64
T/F: Hep A is a lifelong infection
false; NO CHRONIC INFECTION
65
t/F: hEP a causes hepatocellular carcinoma
false
66
Hep A IgG is detected (blank) weeks after infection
1-3
67
T/F: Hep A IgG provides lifelong protection
true
68
How long after infection will Hep A resolve?
2-4 weeks
69
How does one diagnose hep A?
IgM or 4 fold increase in IgG titiers
70
What tissues does Hep A infect?
oropharynx and GI tract
71
What mediates the hepatic injury in Hep A?
CTL action
72
Norwalk virus belongs to what genus?
Norovirus
73
What is the mode of transmission of Norwalk virus?
Fecal-oral route
74
What is the most common cause of VIRAL GE in older kids and adults in the US?
Norwalk virus
75
People on cruise ships or in swimming pools are at a risk to get GE caused by ?
Norwalk virus
76
What cells does Norwalk virus infect?
mucosal cells of GI tract
77
A SUDDEN ONSET OF VOMITING, non-bloody diarrhea, low grade fever and abd. cramping are suggestive of/
Norwalk virus
78
What is the incubation period of norwalk virus
around 24 hours
79
Is the primary diagnosis of norwalk virus lab based or clinical?
clinical
80
What lab test can be done to confirm the clinical diagnosis of Norwalk virus?
PCR on stool samples (only in instances of public health concern)
81
CLOSED or SEMICLOSED communities such as long-term care facilities, overnight camps, hospitals, prisons, dormitories, and cruise ships are hotspots for?
norwalk virus
82
Raspberries, salads, and sandwhiches may be contaminated with (blank)
norwalk virus

Block 6 Week 4 Colt (10 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2025 Bold Learning Solutions. Terms and Conditions