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Microbiology > RNA Viruses > Flashcards

RNA Viruses Flashcards

0
Q

All DNA viruses replicate in the cytoplasm except

A

Inluenza and retrovirus

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1
Q

All RNA viruses have single stranded DNA except

A

Reovirus and rotavirus

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2
Q

Poliomyelitis replicates where

A

Anterior horn of spinal cord

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3
Q

Most common clinical form of polio

A

Abortive poliomyelits

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4
Q

Cowdry type B intranuclear inclusions

A

Polio

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5
Q

Fever, sore throat and TENDER VESICLES in the pharynx

A

Herpangina- coxsackie

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6
Q

Hemorrhagic conjunctiviid

A

coxsackie

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7
Q

Fever and severe pleuritic type chest pain

A

Pleurodynia

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8
Q

Most common cause of myocarditis and pericarditis

A

coxsackie

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9
Q

Most common cause of aseptic meningitis

A

coxsackie

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10
Q

Enteroviruses include

A

coxsackie, poliovirus, echovirus

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11
Q

Orphans because were not initially associated with any disease

A

Echovirus

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12
Q

Only respiratory picornavirus

A

Rhinovirus

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13
Q

Common colds

A

Rhinovirud

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14
Q

Most important test for hepatitis A

A

Anti HAV IgM

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15
Q

Also known as enterovirus 72

A

Hepatitis A

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16
Q

Hepatitis that Causes high mortality in pregnant people

A

E

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17
Q

Most common cause of nonbacterial Diarrhea in adults

A

Norwalk(norovirus)

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18
Q

Most common cause of childhood diarrhea

A

Rotavirus

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19
Q

Most common cause of respiratory tract infection

A

Influenza virus

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20
Q

Responsible for major outbreaks of influenza

A

B

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21
Q

Major changes based on the reassortment of segments of the genome RNA

A

Antigenic shift

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22
Q

Minor changes based on mutation in the genome RNA

A

Antigenic drift

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23
Q

Paramyxoviruses all have what protein

A

Fusion

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24
Q

Warthin finkeldey bodies

A

Measels

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25
Q

Pathognomonic for measles

A

Koplik’s spots

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26
Q

Bright red lesions with a white, central dot on buccal mucosa

A

Koplik spots- measles

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27
Q

Otherwise known as Damson disease

A

Subacute sclerosing panencephalitis- measles

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28
Q

Reduces severity of measles

29
Q

Most common cause of pneumonia and bronchiolitis in infants

30
Q

Croup

A

Laryngotracheobronchitis- parainfluenza virus 1 and 2

31
Q

Steeple sign

A

Parainflueza virus 1 and 2

32
Q

BULLET SHAPED

A

Rabies virus

33
Q

Negri bodies

34
Q

Only vaccine routinely used post exposure

A

Rabies vaccine

35
Q

Horseshoe bat

A

Coronavorus- reservoir

36
Q

Civet cat

A

Coronavirus- reservoir

37
Q

SARS binds to what receptor

38
Q

Dengue virus

A

Flaviviridae

39
Q

Most severe dengue serotype

40
Q

Dengue is diagnosed using

41
Q

Hepatitis C virus

A

Flavivirus

42
Q

Diagnosis of hepa C

A

Anti HCV and HCV RNA

43
Q

Most prevalent blood borne pathogen

44
Q

Main cause of essential mixed cryoglobulinemia

45
Q

Most common indication for liver transpant

46
Q

Enzyme that distinguishes retroviridae from all othet RNA viruses

A

Reverse transcriptase

47
Q

HIV

A

Retrovirus

48
Q

Transmembrane protein of HIV

49
Q

Cone shaped icosahedral core containing the major capsid protein

50
Q

MA (p17)

A

directs entry of double stranded DNA provirus into the nucleus is later essential for process of viral assembly

51
Q

Gene responsible for structure of HIV

52
Q

Gene responsible for enzymes in HIV

53
Q

Gene responsible for envelope proteins in HIV

54
Q

Important serologic marker for HIV infection

55
Q

Most immunogenic region of gp120

56
Q

Mediates fusion of viral envelope with the cell membrane at the time of infection

57
Q

Regulatory gene thy decreases CD4 and class I MHC proteins

58
Q

Period where there is rapid viral replication but HIV test is negativr

59
Q

AIDs occurs at what stage of infection?

60
Q

Most prevalent AIDS defining illness

A

P carinii pneumonia

61
Q

PCP appears at CD4 level of

62
Q

Detects HIV DNA in infected cells

63
Q

Prognostic test for HIV

64
Q

Adult t cell leukemia

A

Human T cell lymphotropic virus

65
Q

Flower shaped nucleus

A

Human T cell lymphotropic virus

66
Q

Thread like viruses

67
Q

Longest virus

68
Q

Self limited febrile illness with progression to neuroinvasivie disease

A

West nile virus

69
Q

Most common cause of epidemic encephalalitis

A

Japanese B virus

70
Q

Thalamic infarcts on CT

A

Japanese B virus

Microbiology (21 decks)

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