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RNA Viruses Flashcards

0
Q

All DNA viruses replicate in the cytoplasm except

A

Inluenza and retrovirus

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1
Q

All RNA viruses have single stranded DNA except

A

Reovirus and rotavirus

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2
Q

Poliomyelitis replicates where

A

Anterior horn of spinal cord

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3
Q

Most common clinical form of polio

A

Abortive poliomyelits

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4
Q

Cowdry type B intranuclear inclusions

A

Polio

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5
Q

Fever, sore throat and TENDER VESICLES in the pharynx

A

Herpangina- coxsackie

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6
Q

Hemorrhagic conjunctiviid

A

coxsackie

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7
Q

Fever and severe pleuritic type chest pain

A

Pleurodynia

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8
Q

Most common cause of myocarditis and pericarditis

A

coxsackie

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9
Q

Most common cause of aseptic meningitis

A

coxsackie

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10
Q

Enteroviruses include

A

coxsackie, poliovirus, echovirus

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11
Q

Orphans because were not initially associated with any disease

A

Echovirus

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12
Q

Only respiratory picornavirus

A

Rhinovirus

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13
Q

Common colds

A

Rhinovirud

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14
Q

Most important test for hepatitis A

A

Anti HAV IgM

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15
Q

Also known as enterovirus 72

A

Hepatitis A

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16
Q

Hepatitis that Causes high mortality in pregnant people

A

E

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17
Q

Most common cause of nonbacterial Diarrhea in adults

A

Norwalk(norovirus)

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18
Q

Most common cause of childhood diarrhea

A

Rotavirus

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19
Q

Most common cause of respiratory tract infection

A

Influenza virus

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20
Q

Responsible for major outbreaks of influenza

A

B

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21
Q

Major changes based on the reassortment of segments of the genome RNA

A

Antigenic shift

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22
Q

Minor changes based on mutation in the genome RNA

A

Antigenic drift

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23
Q

Paramyxoviruses all have what protein

A

Fusion

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24
Warthin finkeldey bodies
Measels
25
Pathognomonic for measles
Koplik's spots
26
Bright red lesions with a white, central dot on buccal mucosa
Koplik spots- measles
27
Otherwise known as Damson disease
Subacute sclerosing panencephalitis- measles
28
Reduces severity of measles
Vit A
29
Most common cause of pneumonia and bronchiolitis in infants
RSV
30
Croup
Laryngotracheobronchitis- parainfluenza virus 1 and 2
31
Steeple sign
Parainflueza virus 1 and 2
32
BULLET SHAPED
Rabies virus
33
Negri bodies
Rabies
34
Only vaccine routinely used post exposure
Rabies vaccine
35
Horseshoe bat
Coronavorus- reservoir
36
Civet cat
Coronavirus- reservoir
37
SARS binds to what receptor
ACE 2
38
Dengue virus
Flaviviridae
39
Most severe dengue serotype
2
40
Dengue is diagnosed using
IgM
41
Hepatitis C virus
Flavivirus
42
Diagnosis of hepa C
Anti HCV and HCV RNA
43
Most prevalent blood borne pathogen
Hepa C
44
Main cause of essential mixed cryoglobulinemia
Hepa C
45
Most common indication for liver transpant
Hepa C
46
Enzyme that distinguishes retroviridae from all othet RNA viruses
Reverse transcriptase
47
HIV
Retrovirus
48
Transmembrane protein of HIV
Gp41
49
Cone shaped icosahedral core containing the major capsid protein
P24
50
MA (p17)
directs entry of double stranded DNA provirus into the nucleus is later essential for process of viral assembly
51
Gene responsible for structure of HIV
Gag
52
Gene responsible for enzymes in HIV
Pol
53
Gene responsible for envelope proteins in HIV
Env
54
Important serologic marker for HIV infection
p24
55
Most immunogenic region of gp120
V3 loop
56
Mediates fusion of viral envelope with the cell membrane at the time of infection
gp41
57
Regulatory gene thy decreases CD4 and class I MHC proteins
Nef nef
58
Period where there is rapid viral replication but HIV test is negativr
Window
59
AIDs occurs at what stage of infection?
Phase 5
60
Most prevalent AIDS defining illness
P carinii pneumonia
61
PCP appears at CD4 level of
<200,000
62
Detects HIV DNA in infected cells
PCR
63
Prognostic test for HIV
PCR
64
Adult t cell leukemia
Human T cell lymphotropic virus
65
Flower shaped nucleus
Human T cell lymphotropic virus
66
Thread like viruses
EBOLA
67
Longest virus
Ebola
68
Self limited febrile illness with progression to neuroinvasivie disease
West nile virus
69
Most common cause of epidemic encephalalitis
Japanese B virus
70
Thalamic infarcts on CT
Japanese B virus

Microbiology (21 decks)

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