DNA viruses Flashcards
Purified nucleic acids of most dsDNA are infectious except
Poxviruses and HBV
All enveloped viruses acquire their envelope from plasma membrane Except
Herpes viruses(nuclear membrane)
All viruses are haploid except
Retroviruses
Reduce expression of antigen presenting cells and inactivate complement
Virokines
Gold standard for viral diagnosis
Presence of viral DNA or RNA
Only live attenuated vaccine that may be given to HIV patients
MMR
All DNA viruses have double stranded DNA except
Parvovirus
All DNA viruses have linear DNA except
Papilloma, polyoma, hepadna
All DNA viruses are icosahedral except
Poxvirus
All DNA viruses replicate in the nucleus except
Poxvirus
Fifth disease
Parvovirus B19
Slapped cheeks
Fifth disease- erythema infectiousun- parvovirus
Aplastic crisis
Parvovirus B19
Hydrops fetalis
Parvovirus B19
Chronic B19 infection
Pancytopenia
Only virus with fiber
Adenovirus
Cowdry type B intranuclear inclusions
Adenovirus
Koilocytes
HPV- cytoplasmic vacuoles
Encode proteins that inactivate tumor suppressor genes
Genes E6 and E7
HPV that causes skin and plantar warts
1 and 4
Most common viral STD
Condylomata acuminata
Condylomata acuminata is caused by what type of HPV
HPV 6 and 11
HPV type that can cause carcinoma of cervix, penis and anus
16,18,31,33
Progressive multifocal leukoencephalopathy
JC polyoma virus
Demyelinating disease that affects oligodendrocytes characterized by deficits in speech, coordination, and memory
Progressive multifocal leukoencephalopathy
Hemorrhagic cystitis and nephropathy
BK polyoma
Site of latency of HSV 1
Trigeminal ganglia
Site of latency of HSV 2
Lumbosacral ganglia
Multinucleated giant cells on tzanck, large, pink to purple intranuclear inclusions(Cowdry type A)
HSV
Herpes of the trunk
Herpes gladiatorin
Site of latency for vzv
Dorsal root ganglia
Multinucleated giant cells with intranuclear inclusions
VZV
Dew drop on a rose petal appearance
Varicella
Reye’s syndrome
Varicella- aspirin for fever
Postherpetic neuralgia
Herpes zoster
Involvement of geniculate ganglion caused facial nerve paralysis
Ramsay hunt syndrome- varicella
Cultured jn shell tubes
CMV
Giant cells with owl’s eye nuclear inclusion
CMV
Most common cause of congenital abnormalities
Congenital CMV infection
Heterophil negative mononucleosis
CMV
Most common cause of blindness in HI
CMV retinitis
Rare complication of EBV
Splenic rupture
Burkits lymphoma
EBV
Nasopharyngeal carcinoma
EBV
Dark purple, flat to nodular; apprear on multiple sites; malignancy of vascular endothelial cells
Kaposi’s sarcoma- HHV 8
Guarneri bodies (Intracytoplasmic eosinophilic inclusions)
smallpox
Small pox is caused by
Variola-poxviridae
Henderson peterson bodies(intracytoplasmic inclusion bodies)
Molloscum contagiosum
Pinkish papular skin lesions with an umbilicated center
Molloscum contagiosun
Only DNA virus that produced DNA by reverse transcription with mRNA as the template
HBV
Polyarteritis nodosa
HBV
Functional renal failure without renal pathology
Hepatorenal syndrome - HBV
Vascular dilatations cause overperfusion relative to ventilation, leading to VQ and hypoxemia
Hepatopulmonary syndrome- HBV
First vaccine to prevent human cancer
HBV vaccine