DNA viruses Flashcards

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0
Q

Purified nucleic acids of most dsDNA are infectious except

A

Poxviruses and HBV

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1
Q

All enveloped viruses acquire their envelope from plasma membrane Except

A

Herpes viruses(nuclear membrane)

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2
Q

All viruses are haploid except

A

Retroviruses

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3
Q

Reduce expression of antigen presenting cells and inactivate complement

A

Virokines

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4
Q

Gold standard for viral diagnosis

A

Presence of viral DNA or RNA

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5
Q

Only live attenuated vaccine that may be given to HIV patients

A

MMR

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6
Q

All DNA viruses have double stranded DNA except

A

Parvovirus

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7
Q

All DNA viruses have linear DNA except

A

Papilloma, polyoma, hepadna

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8
Q

All DNA viruses are icosahedral except

A

Poxvirus

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9
Q

All DNA viruses replicate in the nucleus except

A

Poxvirus

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10
Q

Fifth disease

A

Parvovirus B19

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11
Q

Slapped cheeks

A

Fifth disease- erythema infectiousun- parvovirus

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12
Q

Aplastic crisis

A

Parvovirus B19

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13
Q

Hydrops fetalis

A

Parvovirus B19

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14
Q

Chronic B19 infection

A

Pancytopenia

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15
Q

Only virus with fiber

A

Adenovirus

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16
Q

Cowdry type B intranuclear inclusions

A

Adenovirus

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17
Q

Koilocytes

A

HPV- cytoplasmic vacuoles

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18
Q

Encode proteins that inactivate tumor suppressor genes

A

Genes E6 and E7

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19
Q

HPV that causes skin and plantar warts

A

1 and 4

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20
Q

Most common viral STD

A

Condylomata acuminata

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21
Q

Condylomata acuminata is caused by what type of HPV

A

HPV 6 and 11

22
Q

HPV type that can cause carcinoma of cervix, penis and anus

A

16,18,31,33

23
Q

Progressive multifocal leukoencephalopathy

A

JC polyoma virus

24
Q

Demyelinating disease that affects oligodendrocytes characterized by deficits in speech, coordination, and memory

A

Progressive multifocal leukoencephalopathy

25
Q

Hemorrhagic cystitis and nephropathy

A

BK polyoma

26
Q

Site of latency of HSV 1

A

Trigeminal ganglia

27
Q

Site of latency of HSV 2

A

Lumbosacral ganglia

28
Q

Multinucleated giant cells on tzanck, large, pink to purple intranuclear inclusions(Cowdry type A)

A

HSV

29
Q

Herpes of the trunk

A

Herpes gladiatorin

30
Q

Site of latency for vzv

A

Dorsal root ganglia

31
Q

Multinucleated giant cells with intranuclear inclusions

A

VZV

32
Q

Dew drop on a rose petal appearance

A

Varicella

33
Q

Reye’s syndrome

A

Varicella- aspirin for fever

34
Q

Postherpetic neuralgia

A

Herpes zoster

35
Q

Involvement of geniculate ganglion caused facial nerve paralysis

A

Ramsay hunt syndrome- varicella

36
Q

Cultured jn shell tubes

A

CMV

37
Q

Giant cells with owl’s eye nuclear inclusion

A

CMV

38
Q

Most common cause of congenital abnormalities

A

Congenital CMV infection

39
Q

Heterophil negative mononucleosis

A

CMV

40
Q

Most common cause of blindness in HI

A

CMV retinitis

41
Q

Rare complication of EBV

A

Splenic rupture

42
Q

Burkits lymphoma

A

EBV

43
Q

Nasopharyngeal carcinoma

A

EBV

44
Q

Dark purple, flat to nodular; apprear on multiple sites; malignancy of vascular endothelial cells

A

Kaposi’s sarcoma- HHV 8

45
Q

Guarneri bodies (Intracytoplasmic eosinophilic inclusions)

A

smallpox

46
Q

Small pox is caused by

A

Variola-poxviridae

47
Q

Henderson peterson bodies(intracytoplasmic inclusion bodies)

A

Molloscum contagiosum

48
Q

Pinkish papular skin lesions with an umbilicated center

A

Molloscum contagiosun

49
Q

Only DNA virus that produced DNA by reverse transcription with mRNA as the template

A

HBV

50
Q

Polyarteritis nodosa

A

HBV

51
Q

Functional renal failure without renal pathology

A

Hepatorenal syndrome - HBV

52
Q

Vascular dilatations cause overperfusion relative to ventilation, leading to VQ and hypoxemia

A

Hepatopulmonary syndrome- HBV

53
Q

First vaccine to prevent human cancer

A

HBV vaccine