RNA PART III Flashcards
Ebola virus natural host
fruit bat (Pteropodidae family)
Elbola virus can be transmitted via infected what animal?
Bats or primates
Ebola viurs is under what family?
Filoviridae
Ebola virus targets?
endothelial cells, phagocytes, hepatocytes
Ebola virus incubation period
2-21 days
can progress to DIC, diffuse hemorrhage, shock - high mortality rate (100%)
Ebola virus
Diagnosis ebola virus
ELISA
ANTIGEN TEST
RT PCR
Flaviridae viruses
Dengue virus
Zika virus
Yellow fever Virus
West Nile Vorus
Dengue virus transmission
bite of female Aedes aegypti mosquito (A. albopictus)
Dengue virus spectrum of disease
Dengue fever (Breakbone fever)
Dengue hemorrhagic fever
Dengue virus diagnosis
NS1 antigen, RT-PCR, Dengue IgM and IgG, and CBC (platelet count)
How to confirm dengue virus?
Perform viral culture isolation And PCR
Severe dengue symptoms
Severe plasma leakage
Severe bleeding
Severe organ impairment
Zika virus transmission
Aedes mosquito bites
Zika virus spectrum of disease
conjunctivitis, low-grade fever, muscle and joint pain, headache, and photophobia.
Zika virus complications
microcephaly and Guillain- Barre syndrome
Yellow fever virus reservoir
Monkey or human
Yellow fever virus MOT
bite of Aedes or Haemagogus mosquito
Yellow fever virus spectrum of disease
characterized by jaundice and fever
Prostration and shock occur, accompanied by upper gastrointestinal tract hemorrhage with hematemesis (“black vomit”)
Yellow fever virus
Yellow fever virus diagnosis
Councilman bodies (liver biopsy)
West nile virus transmissio
bites of Culex mosquito
West nile virus spectrum of disease
Encephalitis
acronym for arthropod-borne virus and
highlights the fact that these viruses are transmitted by arthropods, primarily mosquitoes and ticks.
Arbovirus
Most arboviruses are classified in three families, namely
togaviruses, flaviviruses, and bunyaviruses
