Enveloped DNA VIRUS

Question 1

Vesicle filled with virus particles and cell debris

Answer 1

Herpes Simplex Viruses (HSV)

Question 2

Gingivostomatitis
Herpes labialis (lips)
Keratoconjunctivitis
Temporal lobe encephalitis
Herpetic whitlow (fingers)
Herpes gladiatorum (trunk)

Answer 2

HSV-1 (HHV-1)

Question 3

Causes temporal lobe encephalitis

Answer 3

HSV-1 (HHV-1

Question 4

Genital herpes
Neonatal herpes (TORCH)
Aseptic meningitis

Answer 4

HSV-2 (HHV-2)

Question 5

Diagnosis for HSV

Answer 5

Tzanck smear (multinucleated giant cells)

Question 6

is the most common cause of sporadic, fatal encephalitis in the US

Answer 6

HSV-1

Question 7

principal target area of the virus of HSV

Answer 7

Temporal Lobe

Question 8

Chicken Pox

Answer 8

Varicella-Zoster Virus (VZV) / HHV-3

Question 9

• Infects the URT, then spreads via the blood to the skin

Answer 9

Varicella-Zoster Virus

Question 10

HHV-3 Becomes latent in the dorsal root ganglia, which may reactivate as

Answer 10

zoster

Question 11

Unilateral painful vesicular eruption with a dermatomal distribution (thoracic and lumbar)

Answer 11

HERPES ZOSTER / SHINGLES

Question 12

Most common complication of HHV-3

Answer 12

Debilitating pain (postherpetic neuralgia)

Question 13

Varicella-Zoster Virus is also known as

Answer 13

HHV-3 /chicken pox

Question 14

Most common complication of herpes zoster/shingles

Answer 14

Debilitating pain (postherpetic neuralgia)

Question 15

Reactivation of latent VZV residing within geniculate ganglion

Answer 15

RAMSAY-HUNT SYNDROME / HERPES ZOSTER OTICUS

Question 16

Fetuses infected at 6-12 weeks’ AOG: maximal interruption with limb development (short and malformed limbs covered with cicatrix – skin lesion with zigzag scarring associated with atrophy of the affected limb)

Answer 16

Congenital Varicella

Question 17

Fetuses infected at 16-20 weeks’ AOG: eye and brain involve

Answer 17

CONGENITAL VARICELLA

Question 18

Ramsay-Hunt Syndrome: treatment

Answer 18

Treatment

Valacyclovir
Prednisone

Question 19

USES OF ASPIRIN IN PEDIATRIC DISEASES:

Answer 19

• Kawasaki
• ARF
• JRA

Question 20

Most common intrauterine viral infection

Answer 20

CONGENITAL CMV INFECTION

Question 21

Most common infectious cause of congenital abnormalities

Answer 21

CONGENITAL CMV INFECTION

Question 22

Monospot-negative and HETEROPHIL-NEGATIVE MONONUCLEOSIS

Answer 22

CMV

Question 23

owl’s-eye nuclear inclusion

Answer 23

Cytomegalovirus

Question 24

Kissing disease’

Answer 24

Infectious mononucleosis

Question 25

Infects mainly lymphoid cells, primarily B-lymphocytes through CD21

Answer 25

Epstein-Barr Virus (EBV) / HHV-4

Question 26

Differential white blood cells count will show elevated “atypical lymphocytes”

Answer 26

Downey Cells

Question 27

Use of amoxicillin in mononucleosis can cause characteristic

Answer 27

maculopapular rash.

Question 28

most common AIDS-related malignancy

Answer 28

Kaposi sarcoma

Question 29

rose-colored macules appear on body after several days of high fever; can present with febrile seizures; usually affects infant

Answer 29

ROSEOLA / EXANTHEM SUBITUM / SIXTH DISEASE

Question 30

SIXTH DISEASE

Answer 30

Roseola/ Exanthem subitum