Rickettsial Diseases Flashcards

1
Q

What are rickettsial diseases?

A

Range of infections causes by intracellular gram negative bacilli causing small vessel vasculitis
All have fever, head ache and rash

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2
Q

How do you treat rickettsial illnesses?

A

Doxycycline for 1 week

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3
Q

What causes scrub typhus and where do you get it?

A

Orientia tsutsugamushi

SE Asia, Asia, Oceania

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4
Q

What is the vector of scrub typhus?

A

Chigger mite

Trombiculidae

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5
Q

What are the signs/symptoms of scrub typhus?

A
An eschar 5-10 days after bite
Fever, rash (central and macular), headache
Delirium
Hepatosplenomegaly
LNs
Pneumonia
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6
Q

How do you prevent scrub typhus?

A

Wear permethrin clothing

Prophylactic doxycycline for at risk groups

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7
Q

What causes epidemic typhus and where do you find it?

A

Rickettsia prowazekii
Mostly Africa and South America
Areas of over crowding

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8
Q

How does epidemic typhus spread?

A

Body louse
Pediculus humanus corporis

Scratch it’s faeces into skin

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9
Q

What are the symptoms if epidemic typhus?

A
Conjunctive suffusion 
Rash
Headache
Fever
Delirium
Pneumonia
Meningitis
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10
Q

How do you prevent epidemic typhus?

A

Delouse with DDT

In epidemic- mass Tx one off doxy dose, boiling of clothes and bedsheets

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11
Q

What causes murine/endemic typhus and where is it found?

A

Rickettsia typhi

Worldwide

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12
Q

What are the symptoms of murine typhus?

A
Eschar
Headache
Fever
Rash
Hepatosplenomegaly
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13
Q

What spreads murine typhus?

A

Rat flea

Xenopsylla cheopis

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14
Q

How do you identify a rat flea?

A

Meral rod present

No pronotal or genal comb

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15
Q

What causes African tick typhus and where is it found?

A

Rickettsia africae

Central/South Africa and West Indies

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16
Q

What are the symptoms of African tick typhus?

A
Eschar
Headache
Fever
Rash
Virtually no mortality
17
Q

What are spotted fevers and how are they spread?

A

Tick typhus
Hard ticks
Amblyoma

18
Q

Where is Rocky Mountain spotted fever found and what causes it?

A

USA

Rickettsia ricketsii

19
Q

How can you tell a hard tick from a soft one?

A

Can see mouthparts and leg bases from above

20
Q

How can you identify a body louse?

A

6 legs
Bigger and lighter than a head louse
Abdominal indentations are more shallow

21
Q

What is the genus of hard tick that spreads typhus?

A

Amblyomma

Family: ixodidae