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Tropical Bacteria > Cholera > Flashcards

Cholera Flashcards

1
Q

What causes cholera?

A

Vibrio cholerae

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2
Q

What are the characteristics of vibrio cholerae?

A

G-ve comma shaped
Motile
Aerobic

Multiple serotypes with different case:carriers ratios

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3
Q

How is cholera spread?

A

Transmitted by water contaminated with faeces

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4
Q

What is the pathophysiology of cholera?

A

Toxin produced which produces cAMP in gut mucosa and leads to Cl and H2O being effluxed into lumen

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5
Q

What are the symptoms of cholera?

A

Profuse rice water diarrhoea
80% vomiting

75% have no symptoms
If severe D+V can lead to hypovolaemic shock

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6
Q

How do you manage cholera?

A

Volume replacement- match the output with salty sugar water
Zinc for children
Doxycycline prevents further spread but no effect on toxin

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7
Q

How do you prevent cholera?

A

WASH

Vaccine: oral live attenuated, 2doses, lasts 2yrs and can be used as PEP

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Tropical Bacteria (19 decks)

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