Meliodosis Flashcards

1
Q

What causes meliodosis and where is it found?

A

Burkholderia pseudomallei

Northern Australia, SE Asia especially Thailand

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

What does burkholderia pseudomallei look like?

A

G-ve bacilli with bipolar staining

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

How is meliodosis transmitted and how long is its latency period?

A

Contamination of cut with water
Inhalation of aerosolised water
Aspiration of water

1-21 days

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

What are the risk factors for meliodosis?

A

Diabetes
Alcohol
Immunosuppression
Renal disease

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

What clinical syndromes can you get in meliodosis?

A
Asymptomatic- common
Neuro
Parotitis - 1/3 kids
Pneumonia- 50%
Prostate abscess
Osteomyelitis 
Septicaemia 
Derm- eryhematous lesion
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

How do Ohio diagnose meliodosis?

A

Blood cultures

Serology but will be positive if from endemic country

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

How do you treat meliodosis?

A

Very resistant
Meropenem or ceftazidime for 2weeks
Daily doxy and cotrimox for 3 months to eradicate

How well did you know this?
1
Not at all
2
3
4
5
Perfectly