Brucellosis Flashcards
What causes brucellosis and what are the associated animals?
Brucella melitensis - goats/sheep
Brucella abortus - cattle
G-ve intracellular coccobacillus
Where does brucellosis occur?
Middle East, Mediterranean, Mongolia
How is brucellosis transmitted?
Unpasteurised milk/cheese
Inhalation
Breast milk
Blood products
Who are the at risk populations of brucellosis?
Vets
Lab workers
Farmers/ slaughterhouse
What are the symptoms of brucellosis?
Undulant fever Myalgia MSK- sacroiliitis and osteomyelitis GI- hepatosplenomegaly and liver abscesses GU- orchitis Endocarditis
How do you diagnose brucellosis?
Blood/BM culture
Serology
Histology: granulomas with lymphocytic infiltrates
How do you manage brucellosis?
Doxy and Rifampicin for 6wks
Longer if CNS/joint/cardio
How do you prevent brucellosis?
Vaccinate animals
PPE for high risk groups
Lab precautions
Pasteurise milk